Protein Alignment Hnf4 and nhr-172

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504933.2
• Gene: nhr-172 / 183808
• WormBaseID: WBGene00016927
• Length: 311
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 73/328 - (22%)
• Similarity: 136/328 - (41%)
• Gaps: 54/328 - (16%)

  Fly   193 FFRRSVRKNHQYTCRFARNC--VVDKDKRNQCRYCRLRKCFKAGMKKEAVQN---ERDRISCRRT 252
            ||||::.:|..:.|:...||  |.......:|..||.::|.:.|||.....|   |.:.....:.
 Worm     2 FFRRAIVENPFFNCKKLNNCYEVSTNSNHLKCAACRFKRCLQLGMKLPPSNNAILELENQKAHKL 66

  Fly   253 SNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEW 317
            ..    ..|||.:....:.|   |........:|::.:.|.||:..: ||    ..:..:|..||
 Worm    67 KK----LLNGLILRDAKRCE---RHLTFYTRSDPSLEDILINKKTMN-ND----KNENAVTSFEW 119

  Fly   318 AKQIPAFN------------ELQLDDQVALLRAHA-GEHLLLGLSRRSMHLKDVLLLSNNCVITR 369
            : .:..||            .|:..|:..|.:.:. ..::|.|..|.....:..::......|
 Worm   120 S-FLAVFNVIEYFSTFDFIENLEYSDKKLLFQCNTFNANVLCGAMRGFKEKRSKMVTPTGQAI-- 181

  Fly   370 HCPDPLVSPNLD-ISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLR 433
             .||. ::|.|: .|::..|:..:::.::.::.:.:.||..:. |:||......|:|..:|....
 Worm   182 -LPDG-IAPLLNTTSQMLHRVSCQVIAIIIELKMTNEEFILLN-LIFFLRIDNNLSESAKISLAS 243

  Fly   434 HQ--ILNNLEDYISDRQYESR--GRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEM 494
            ||  ..|.|.:| ...:||.|  .||.::|.:..::|..:.:|       |..|:     :||..
 Worm   244 HQNFFTNALFEY-CQLKYERRAPSRFADLLSLCQIIQKTSSEM-------KYIGI-----MLQTF 295

  Fly   495 LLG 497
            :.|
 Worm   296 VPG 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	18/56 (32%)
		NR_LBD_HNF4_like	264..494	CDD:132729	51/247 (21%)
nhr-172	NP_504933.2	ZnF_C4	<1..47	CDD:197701	14/44 (32%)
		HOLI	120..281	CDD:214658	35/167 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910