Protein Alignment Hnf4 and nhr-170

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_507673.2
• Gene: nhr-170 / 183795
• WormBaseID: WBGene00008309
• Length: 420
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 85/409 - (20%)
• Similarity: 148/409 - (36%)
• Gaps: 106/409 - (25%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTC-RFARNCVVDK-DKRNQCRYCRLRKCFK 232
            |.||...:.|.|:|..:|..|..||||:|..|.:|.| :....|.:.. .:...|::||.:||..
 Worm    17 CEICQKTSHGLHFGLETCRACAAFFRRTVVLNRKYKCIQKTGKCEIGAGGEEKLCKFCRFKKCID 81

  Fly   233 AGMKKEAVQNE-RDRISCRRTSNDDPDPGNGLSVIS----LVKAEN------------------- 273
            .||..|.|:.: :|  ....||:..|...:.:.|.|    :.|..|
 Worm    82 LGMTTENVRTDFKD--DSEDTSSQSPQSTSSMEVTSSQQIVAKVRNRVEYYIVNPKTQAPAMLID 144

  Fly   274 ------ESRQSKAGAAMEPNI--NEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFN----- 325
                  |||     |.:|.:.  :|||    .|.:|.: :.|...|..:.|.....|.|.
 Worm   145 VNAIIKESR-----AILETHYFPDEDL----IAHLNPL-QRMSHSLHKIREKQSWSPEFFEHVKF 199

  Fly   326 -------ELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLL--------SNNCVITRHCPDPL 375
                   |:|:.|....| .|:.|...|....:....|.|..:        .:..:..:.|.|..
 Worm   200 YKMFQWWEVQMRDTATWL-MHSDEFRRLPSHEKIAIFKIVWAVWRRFERYTMSAQMFGQKCYDEK 263

  Fly   376 V------------SPNLDISRI------------GARII---DELVTVMKDVGIDDTEFACIKAL 413
            :            :.::|.|.:            |.::|   |.:|....::.:.:||...|...
 Worm   264 IHVHNHQFAARFGNYHIDYSNVSDHGFERFNNVFGGKMIRYFDIIVKPYLELNLSETEVTYILCQ 328

  Fly   414 VFFDPNAKGLNEPHRIKSLR--HQILNNLEDYISD--------RQYESRGRFGEILLILPVLQSI 468
            :.::...:.|....:....|  .:|.|||..|..:        :.|.|  |..:::.|:..:.||
 Worm   329 IVWNYAGRRLQGQTQAAGERFLEEISNNLHSYYEEAARKEENPKNYAS--RLTKMMQIVNEMLSI 391

  Fly   469 TWQMIEQIQFAKIFGVAHI 487
            ..:....:..|.:|.:.:|
 Worm   392 QLKRENTMDIAMLFDMFNI 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	26/77 (34%)
		NR_LBD_HNF4_like	264..494	CDD:132729	55/312 (18%)
nhr-170	NP_507673.2	ZnF_C4	16..87	CDD:197701	24/69 (35%)
		Hormone_recep	187..397	CDD:278530	35/212 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910