Protein Alignment Hnf4 and nhr-169

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_493156.2
• Gene: nhr-169 / 183768
• WormBaseID: WBGene00008289
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 79/390 - (20%)
• Similarity: 139/390 - (35%)
• Gaps: 112/390 - (28%)

  Fly   158 LQQQQQQQSPTVCAICG-DRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQ 221
            |:...::.:..:|::|. ......|:|...|..|..||||:|..|..|.|:....|   |..|..
 Worm     7 LEMPFRESTDPICSVCNFSSLIAPHFGGLVCSACASFFRRTVALNIHYLCKKDNQC---KGMRKN 68

  Fly   222 CRYCRLRKCFK-AGMKKEAVQNERDRISCRRTSNDDP--------DPGNGLSVISLVKAENESR- 276
            ||.||...|.| ||||:..|:.       |:..|:.|        :.|| ..|:....:.|::|
 Worm    69 CRACRFESCVKIAGMKRSLVKE-------RKNLNNIPLYILNRRNETGN-QGVVRAFVSSNQNRL 125

  Fly   277 --QSKAGAAMEPNINEDLS----------------------NKQFASINDVCESMKQQLLTLVEW 317
              :.......|..||:::.                      .||| .:|.:....|::|..:|.:
 Worm   126 ENRLSLSPLTELPINDEMDVSKILKTTPSSLLKYYVEQVSHGKQF-YMNTLNIRTKEELFEIVSY 189

  Fly   318 AKQIPAFN-------ELQLDDQVALLR----------------------AHAGEHLLLGLSRRSM 353
            ..::.|..       :|..:..:.:||                      ::..|...:.|.....
 Worm   190 QSKVAAETCRTCPGVDLLDNRDILILRKYFQFSNIWIESTWKYWFSNDFSNDTEKFDIKLMEFIG 254

  Fly   354 HLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDP 418
            .:|..||:|                   :||:...|.:  .|..|.:        ||..||:.:.
 Worm   255 QVKSTLLIS-------------------LSRLKFNIFE--FTAFKAI--------CIWKLVYHET 290

  Fly   419 N-AKGLNEPHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIF 482
            : |..:......:.:...:::..:.|......|...|.|||.|::    |..:||...:  ||::
 Worm   291 SRAMKIVAQEHYEGVTKALISYYQTYTLLDSMEIAIRVGEITLLV----SSVFQMYHDM--AKLY 349

  Fly   483  482
             Worm   350  349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/76 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	45/274 (16%)
nhr-169	NP_493156.2	ZnF_C4	18..86	CDD:197701	27/70 (39%)
		HOLI	188..341	CDD:214658	28/185 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910