Protein Alignment Hnf4 and nhr-129

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001122887.1
• Gene: nhr-129 / 183635
• WormBaseID: WBGene00003719
• Length: 420
• Species: Caenorhabditis elegans
• Alignment Length: 387
• Identity: 90/387 - (23%)
• Similarity: 147/387 - (37%)
• Gaps: 120/387 - (31%)

  Fly   165 QSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNC--VVDKDKRNQCRYCRL 227
            :.|..|.:||..|:|.||...:|:|||.||||.|.....:||:...:|  :..:|...:||.||:
 Worm    25 ERPKDCFVCGGSASGYHYDVPACNGCKTFFRRYVISKRLFTCKLNDDCFDLSTRDVPVKCRACRI 89

  Fly   228 RKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDL 292
            .|||..||...|::.::....|.:                    |...|::..|       |:.:
 Worm    90 NKCFAVGMNPHALEVDKTNTDCLK--------------------EVTKRKNMIG-------NDAV 127

  Fly   293 SNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDD-QVALLRAHAGEHLLLGL-----SRR 351
            :.||.. :|.: |||:.::..:.:    :..:.||:||. :.:....|..|  :.||     |..
 Worm   128 NEKQLV-LNSL-ESMENKIQKIAD----MLTYLELKLDQFRASSYNPHWAE--VRGLEFVLNSTN 184

  Fly   352 SMHLKDVL-------LLSNNCVITRHCPDPLVSPNLDIS---------------RIGARI----- 389
            .:.|.|..       ||.||...:|  |.||....|.|.               .:.|.|
 Worm   185 RISLADKFGPMPGWPLLDNNLSPSR--PPPLSHEKLVIGGPPPYSPKKKHWLYFNMLATIEYAKT 247

  Fly   390 ---IDELVTVMKDVGIDDTEFACIKALVFFDPNAK---------GLNEPHRIKSLRHQILNNLED 442
               ..||:...:.:.|..|..||:..||.|...:|         |..:.||          |.|.
 Worm   248 FMFFHELLPRDQLILIRYTTLACVNLLVSFSSVSKKYDTAVHPDGTLQMHR----------NQEY 302

  Fly   443 YISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVA-----------HIDSLLQE 493
            |.|:           ::.|:|:::    ..::||::..:..:.           |...||.|
 Worm   303 YSSN-----------VMSIIPLIR----YQVQQIEYVLLKAICLCNPAVPDLSKHAQLLLAE 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/76 (39%)
		NR_LBD_HNF4_like	264..494	CDD:132729	58/286 (20%)
nhr-129	NP_001122887.1	ZnF_C4	30..99	CDD:197701	29/68 (43%)
		HOLI	236..386	CDD:214658	27/139 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010