Protein Alignment Hnf4 and nhr-161

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504765.2
• Gene: nhr-161 / 183178
• WormBaseID: WBGene00016364
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 380
• Identity: 83/380 - (21%)
• Similarity: 141/380 - (37%)
• Gaps: 100/380 - (26%)

  Fly   169 VCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYT-CRFARNCVVDKDKRNQCRYCRLRKCFK 232
            :|.||...:|..|:|..||..|..||||.|....|.| |    ||..|   |..|||||::.|.|
 Worm     2 LCKICDGPSTEYHFGCPSCRACAAFFRRYVNSPKQLTEC----NCETD---RVPCRYCRMKLCLK 59

  Fly   233 AGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENE--------------SRQ--SKAG 281
            |||....||.:||...||.:.       :||...|:....|:              .|:  .|..
 Worm    60 AGMMISKVQQKRDNNPCRLSV-------SGLETTSIPLRNNDRIFTALENYRWLTKERKIVHKTS 117

  Fly   282 AAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAG----- 341
            .|.:.|..|      ::|| .:.:|.       :.|......|.||::.|.:......:.
 Worm   118 PAKKVNFYE------YSSI-AIIDSR-------IVWNLLERTFLELKVLDDIDKFNLFSNFYPKW 168

  Fly   342 ---EHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRI------GARIID-ELVTV 396
               |..:..|.:..:|             |...|:.  .|...||:.      |.|:.| |::.:
 Worm   169 TLFESAITALQKSDVH-------------TFFAPNG--KPAQQISKFYKDCMTGLRMKDTEVLRI 218

  Fly   397 MK---------------DVGIDDTEFACIKALVFFDPNAKGLNEP-----HRIKSLRHQILNNLE 441
            .:               ::..|..|...:.||:..||....:::.     ||.:.:   |...|:
 Worm   219 FEPYWNSYYSHVAYPLFELKFDQMEHMALLALMLMDPGYTNISDECVEMCHRFRKV---IQMELK 280

  Fly   442 DYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLL 496
            .|..::..:.. |..:::..|.:::.......|::....::.|. :|...:.|::
 Worm   281 GYYLEKNSDPE-RILKVIEALLLMEKADQWFQEEVHMCGVYNVT-VDDDFRRMVM 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	33/75 (44%)
		NR_LBD_HNF4_like	264..494	CDD:132729	43/280 (15%)
nhr-161	NP_504765.2	ZnF_C4	2..65	CDD:197701	31/69 (45%)
		Hormone_recep	114..313	CDD:278530	37/231 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910