Protein Alignment Hnf4 and nhr-159

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504069.2
• Gene: nhr-159 / 182732
• WormBaseID: WBGene00015902
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 371
• Identity: 87/371 - (23%)
• Similarity: 167/371 - (45%)
• Gaps: 69/371 - (18%)

  Fly   167 PTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCV----VDKDKRNQCRYCRL 227
            |..|.:|...|...:||..:||.||.||||.|.:..:|||:.:.||.    .|.....:|:.||.
 Worm    16 PRKCLVCYRPAYCNNYGVLTCDACKMFFRRVVTEKLEYTCKCSNNCFEGFSEDSTIYPKCKSCRY 80

  Fly   228 RKCFKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVI-SLVKAENESRQS--KAGAAMEPNIN 289
            ::|.|.|| ..|.:.::..:..|...:|:.|     ::| .|...:|..|::  .......|.:.
 Worm    81 QECLKFGM-NYAFRKQKRLLEIRNKKDDELD-----AIIDGLRYLDNHRRETLRTKFTISNPTLQ 139

  Fly   290 EDLSNKQFAS-INDVCESMKQQ------LLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLG 347
            |.:..|...: :....|.::.|      |.|.||:...:|..::||..:::.|||..|.:..|..
 Worm   140 EMVEKKGLETYVKTPKEQLRPQDWSFFALYTTVEFLSNMPFMSKLQTAEKMCLLRNSASKCSLFA 204

  Fly   348 LSRRSMHLKDVLLLSNNCVITRHCPDPLVSPN--LD-----------ISRIGARIIDEL--VTVM 397
            .:.||.:.|...:      ||....|  :.||  ||           :.||.:.::.:|  :||:
 Worm   205 GAMRSFNEKKAEM------ITVDGQD--IYPNSILDFVGSSGGAREFLGRIKSMVVGKLAELTVL 261

  Fly   398 KDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISDR------QYESRG--R 454
            ::      ||..|.:::|.:|:.  ..||.. .:.:.::.:..:::.:..      :|...|  |
 Worm   262 RE------EFLLISSIIFCNPDV--FYEPEN-SAAQSKVASQQQEFTAALLHFCMCKYGLNGPSR 317

  Fly   455 FGEILLILPVLQSITWQMIEQIQF-AKIFGVAHID----SLLQEML 495
            |.::|.:.|::|    :..:.:|| ..:|.:...|    ::::|::
 Worm   318 FTQLLSLCPIIQ----RNFDDLQFLTMMFRMKRADIKFRNIVEELI 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/78 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	54/267 (20%)
nhr-159	NP_504069.2	ZnF_C4	18..89	CDD:197701	27/71 (38%)
		HOLI	164..330	CDD:214658	41/186 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910