Protein Alignment Hnf4 and nhr-257

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_494672.2
• Gene: nhr-257 / 182697
• WormBaseID: WBGene00015869
• Length: 331
• Species: Caenorhabditis elegans
• Alignment Length: 352
• Identity: 80/352 - (22%)
• Similarity: 134/352 - (38%)
• Gaps: 78/352 - (22%)

  Fly   170 CAICGD-RATGKHYGASSCDGCKGFF-RRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFK 232
            |.||.| ..|..|:||..|..|..|| |.:|.|   :.|.....||:...|:..||.||...|.:
 Worm     8 CRICNDPETTSPHFGAIVCTACASFFGRTTVDK---FRCIANNKCVISCAKKITCRSCRYDSCIR 69

  Fly   233 AGMK----------KEAVQNERDRISCRRTSNDDPD---------------PGNGLSVISLVKAE 272
            |||.          |:.|..|.|:......|...|:               |.|.:....:.:.|
 Worm    70 AGMNKFYIRKIKAPKQQVIQEVDQNKTFPNSEMLPNFTRENSHKFSEVLNLPNNEILQFYVKEVE 134

  Fly   273 NESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLR 337
                  |:.:..:.|.::::.|.:  ||||:.........:.:|...|.|..|.|:.:|....||
 Worm   135 ------KSLSLKKRNFSKNILNAE--SINDLLIISAHLTGSAMESCFQCPGINLLEKEDIQVFLR 191

  Fly   338 AHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVG- 401
            .....::.:.      .|::..|:|:             |.|.:|||...:::..:..|...:|
 Worm   192 YFEFSNVWID------SLREYSLMSH-------------SHNKEISRTDKKVMKFINQVKSTLGT 237

  Fly   402 ------IDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQIL----------NNLEDYISDRQYE 450
                  ::..|||..|:...::......::..||.:..|.:.          |.|:  :||  .|
 Worm   238 ALIHLKLNIYEFAAFKSFCIWNIKFHKTSQTMRIVAQGHYVAVSSALRVYYKNQLK--LSD--ME 298

  Fly   451 SRGRFGEILLILPVLQSITWQMIEQIQ 477
            ...|.|:|.|.:..:.:|...:|...|
 Worm   299 IAIRIGDITLQIATVSTIYHDLIRLYQ 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/86 (35%)
		NR_LBD_HNF4_like	264..494	CDD:132729	45/231 (19%)
nhr-257	NP_494672.2	ZnF_C4	7..74	CDD:197701	27/68 (40%)
		HOLI	167..316	CDD:214658	34/171 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910