Protein Alignment Hnf4 and nhr-136

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_506039.2
• Gene: nhr-136 / 182566
• WormBaseID: WBGene00003726
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 403
• Identity: 92/403 - (22%)
• Similarity: 156/403 - (38%)
• Gaps: 101/403 - (25%)

  Fly   140 PNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQY 204
            ||.:.:...|..:|.:.|.....:...|:.|.:|...|||.||...||:|||.|||||:....:|
 Worm    23 PNMDENLEDSKPSSLKYQKAMMSRGTCPSNCKVCRHSATGYHYDVPSCNGCKTFFRRSILDGRKY 87

  Fly   205 TCRFARNCV-----VDKDKRNQCRYCRLRKCFKAGMKKEAVQNE---------RDRISCRRTSND 255
            ||...|.|:     ||..:| .||.||..||.:|||...|:|.:         |..|..::.:..
 Worm    88 TCLKMRKCLSGTEPVDLSRR-MCRACRFEKCVEAGMNPSAIQADMKTTDGELLRKEIMIKQKTAV 151

  Fly   256 DPDPGNGLSVISLVKAENESRQSKAG--AAME-----------PNINEDLSN------------- 294
            |     .|:...::.:..:..|...|  ..||           |..|.|:..
 Worm   152 D-----FLNTPQVIMSFEDKVQGIIGKLTVMELKIEPLYTGGLPPGNRDIRKLDELIDAPLILSY 211

  Fly   295 ------KQFASINDVCESMKQQ--------LLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLL 345
                  |...|::::...:|..        .|..:|::|.....:::.:..:..|:: ||
 Worm   212 DEIPNLKYCPSVDELTGEIKPSGACYIHCGYLASIEYSKMFDFAHKIDVASKATLIK-HA----- 270

  Fly   346 LGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDIS-----RIG-------ARIIDELVTVMK 398
                  ::...|::....:  ..:...|.|:.||...:     |.|       |.:...|.||::
 Worm   271 ------TIMCADIMTAFFS--YYQRKSDRLIHPNGMFAGPPKYRYGEAGTKYQASMQRTLATVLR 327

  Fly   399 DVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSLRHQILNNLEDYISD------RQYES---RGR 454
            . .::..|:..:||:|..:|....|:     .|::..|....|:|:..      ..|.|   ..|
 Worm   328 H-ELNRIEYMLLKAIVLCNPAVSSLS-----ISVQQIIGKEREEYVRTLLTYCLLNYGSVHGPSR 386

  Fly   455 FGEILLILPVLQS 467
            |..:|.|:.||:|
 Worm   387 FSALLAIMSVLES 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	36/88 (41%)
		NR_LBD_HNF4_like	264..494	CDD:132729	46/265 (17%)
nhr-136	NP_506039.2	NR_DBD_HNF4A	53..128	CDD:143518	35/75 (47%)
		HOLI	243..400	CDD:214658	36/177 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010