Protein Alignment Hnf4 and nhr-154

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_506037.2
• Gene: nhr-154 / 182565
• WormBaseID: WBGene00007547
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 414
• Identity: 95/414 - (22%)
• Similarity: 167/414 - (40%)
• Gaps: 109/414 - (26%)

  Fly   134 NNSMFSPNNNLSGSGSGTNS---SQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFR 195
            :..:|...|..|.|....:|   .::..:...:.:.|:.|.:|.:.|.|.||...||:|||.|||
 Worm    44 DQEVFQNQNEFSASPPDISSPFADEKIYKSLPRNKCPSKCLVCRNPAIGYHYDVPSCNGCKTFFR 108

  Fly   196 RSVRKNHQYTCRFARNCV-----VDKDKRNQCRYCRLRKCFKAGMKKEAVQNE---------RDR 246
            |::....::||...:.|:     ||..|| .||.||..||.:.||...|:|.|         |..
 Worm   109 RTIITGRKFTCAKQKKCMDGTEPVDMSKR-LCRACRFAKCVEVGMNPMAIQAEVKTDEGKVLRSE 172

  Fly   247 ISCRRTSNDDPDPGNGLSVI-SLVKAENE--SR--------QSKA----GAAMEP------NINE 290
            :..:|.|         |.|: ||:..|.:  ||        :||.    .:.|.|      .:.|
 Worm   173 VLNQRES---------LGVVSSLIVTEEDLLSRMIEKLTFVESKVEPLHRSGMPPGYRDIRKLEE 228

  Fly   291 DLSNKQFASINDV---------CESMKQ-----------QLLTLVEWAKQIPAFNELQLDDQVAL 335
            .|.:|....:.|:         |.:.|:           ..|..:|.:|.....::|.|:.::.|
 Worm   229 ILDSKPVLVVTDIPNLKFCPSPCANEKRPRRHFTNYVHTSYLASLESSKMFEFSSQLDLESRILL 293

  Fly   336 LRAHAGEHLLLGLSRRSMHLKDVLLLSN-----------NCVITRHCPDPLVSPNL-------DI 382
            :: ||                 .|:.||           ...|.|| ||..:|.::       |:
 Worm   294 MK-HA-----------------TLICSNMMNAFFSINEMKSDILRH-PDGSMSGHMRKFDRENDV 339

  Fly   383 SRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHR--IKSLRHQILNNLEDY-- 443
            .....::|.:.:....:..:|..|:...||::..:|...||:..::  |:..|:|.:..|.:|
 Worm   340 MTDHVKLIQKTLITFLNHKVDKIEYLLFKAIMLCNPAVPGLDSWNQEIIEKERNQYVKALLNYCL 404

  Fly   444 ISDRQYESRGRFGEILLILPVLQS 467
            :...:.:...||..||.:.|::::
 Worm   405 LQHGKLQGPTRFATILAMAPIIEN 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	33/88 (38%)
		NR_LBD_HNF4_like	264..494	CDD:132729	52/267 (19%)
nhr-154	NP_506037.2	NR_DBD_HNF4A	83..160	CDD:143518	32/77 (42%)
		HOLI	266..429	CDD:214658	36/182 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010