Protein Alignment Hnf4 and nhr-76

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_499961.2
• Gene: nhr-76 / 182276
• WormBaseID: WBGene00015497
• Length: 480
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 98/463 - (21%)
• Similarity: 176/463 - (38%)
• Gaps: 129/463 - (27%)

  Fly   131 SNNNNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAIC-GDRATGKHYGASSCDGCKGFF 194
            |:|.|:...|:...:.|...:.||.....::::      ||:| ...::|.|:|..:|..|..||
 Worm    45 SSNPNAYMKPSPPSAISSPPSTSSCSSASEKKE------CAVCKNPNSSGYHFGCIACAACSAFF 103

  Fly   195 RRSVRKNHQYTCRFARN------CVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTS 253
            ||:|..:.:|.||  |:      |.:|:..|:.||.||..:|...||...:|||.||.|..|..:
 Worm   104 RRTVVLSRRYYCR--RDPVGNSLCPLDRRHRSNCRACRYVRCIDMGMNPSSVQNLRDSIKPRSPA 166

  Fly   254 N--------------DD-----PDPGNGLS------------------------VISLVKAENES 275
            .              ||     ..||:.:|                        :.:|.|...|.
 Worm   167 EMIQEAEEEDKKEKLDDILFSAATPGSWISSTSTCNEPLPVAPKEIPGENYIETLAALYKNSVER 231

  Fly   276 RQ------------SKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQ 328
            |:            ...|..|.|...::...|         |.|:.:|:..||....:..|.::.
 Worm   232 RRMFYCNGSLREMLGGTGLKMRPTRFDERYYK---------EKMRFELVLYVEMMNSMSVFRQMD 287

  Fly   329 LDDQVALLRAHAGEHLLLGLSRRSMHLK-DVLLLSNNCVITRHCPDPLVSPN---LDISRIGARI 389
            ||.:..|::..|..  |..|.:..:.:| |.|....           |::|:   .|:|..||:.
 Worm   288 LDTKETLVKGCAVS--LAMLEKYYISVKYDGLRTQK-----------LIAPDGSYTDLSDHGAQF 339

  Fly   390 IDELVTVMKDV----------------------------GIDDTEFACIKALVFFDPNAKGLNEP 426
            .||...:.:.|                            .:.||||..:.|::.|:..|..|::.
 Worm   340 DDEFTQITESVMDKETCLKLLYDPLRSCLNELGSALEHSRMTDTEFCALFAILLFNTAADNLSDA 404

  Fly   427 HR--IKSLRHQILNNLEDYISDR---QYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAH 486
            .|  :...|::::.:..::.:.:   .:|:....|..||:|..:::......|.....::|.|..
 Worm   405 SRNAVVMARNRVMKDWFEFYAKQGIDPHEAGLLVGNTLLLLTAVRNAMAVHRENFHVIRVFNVME 469

  Fly   487 IDSLLQEM 494
            .|.|:.::
 Worm   470 YDKLIDDL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/81 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	53/302 (18%)
nhr-76	NP_499961.2	ZnF_C4	78..151	CDD:197701	27/74 (36%)
		HOLI	266..428	CDD:214658	33/174 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010