Protein Alignment Hnf4 and nhr-79

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_507734.4
• Gene: nhr-79 / 180265
• WormBaseID: WBGene00003669
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 102/467 - (21%)
• Similarity: 163/467 - (34%)
• Gaps: 154/467 - (32%)

  Fly   170 CAIC-GDRATGKHYGASSCDGCKGFFRRSVRKNHQYTC--RFARNCVVDKDKRNQCRYCRLRKCF 231
            |.:| ...||..|:||.||..|..|||||:..:..|.|  ....:|.:|...|..||:|||:||.
 Worm     6 CMVCDSPNATNYHFGAQSCKACAAFFRRSIAMDQCYECLGDGVHSCKIDHTLRLNCRHCRLKKCQ 70

  Fly   232 KAGMKKEAVQNER----DRISCRRTSN----------DDPDPGNGLSVISLVKAENE-------- 274
            ||||.::.||.:|    |:....|.|:          :.|.|.|.........:|||
 Worm    71 KAGMMRDLVQAKREIKSDKGKNSRNSSQSEDFFSPPPEQPGPSNYFDQFPWQASENEMDPYPSSP 135

  Fly   275 ---------------------------------------SRQSK--------------------A 280
                                                   ||.:.                    |
 Worm   136 KIRKMSENLMGIDELQQFIQIPAGVDDFPDIFTDSDEIRSRMTSISEASAYVTGMEEEERLFGLA 200

  Fly   281 GAAMEPNINEDL------SNKQFASIND---VCESMKQQL----------------LTLVEWAKQ 320
            |...|..||.::      :::...|:.|   ||...|..|                ..::::..:
 Worm   201 GLYTEQVINLNMRRRITYTDRLLGSVFDAPCVCPYDKADLKLFDHRTYRQKNRNDYTMILDYINR 265

  Fly   321 IPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHL---KDVLLLSNNCVITRHCPDPLVSPNLDI 382
            .|.|..|...::..|.|..|...:||..|..|..:   :|||:.:|...:..: |.|.|....|.
 Worm   266 FPEFESLSKSEKTVLFRTAAAVDVLLDQSYYSQVIFPTEDVLVTANGEYLPMN-PMPKVENQRDS 329

  Fly   383 SRIGARIIDE------LVTVMK--------------DVGIDDTEFACIKALVFFDPNAKGLNEPH 427
            ....:   ||      ::|.||              |:.:  .||:..|||..:..|.      :
 Worm   330 GNFHS---DEDYDRFKMLTSMKVRQWLHVCEPMKKLDMSL--AEFSLFKALTIWHYNY------Y 383

  Fly   428 RIKSLRHQILNNLEDYI--------SDRQYESR-GRFGEILLILPVLQSITWQMIEQIQFAKIFG 483
            :::....||.:...|.|        .|..::|. .|..||:|.:.:..:...:|:.......::.
 Worm   384 KLQCTGKQICSRQRDDIFRTLLLICDDEGHDSALIRASEIVLAVGIAMAEVHEMVTSYIEITVYD 448

  Fly   484 VAHIDSLLQEML 495
            |.. |.:|::||
 Worm   449 VLD-DPILKDML 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	34/81 (42%)
		NR_LBD_HNF4_like	264..494	CDD:132729	60/353 (17%)
nhr-79	NP_507734.4	ZnF_C4	5..77	CDD:197701	31/70 (44%)
		HOLI	253..429	CDD:214658	40/187 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910