Protein Alignment Hnf4 and nhr-112

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001024286.1
• Gene: nhr-112 / 180115
• WormBaseID: WBGene00003702
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 355
• Identity: 80/355 - (22%)
• Similarity: 137/355 - (38%)
• Gaps: 83/355 - (23%)

  Fly   169 VCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKA 233
            :|.|||...:..|:|.:||..|..||||..   |.........|...:...:.||.||:|||::|
 Worm     1 MCKICGSSESEPHFGGTSCRACAAFFRRFY---HSKKLGLKCTCKTRQSNAHPCRSCRIRKCYEA 62

  Fly   234 GMKKEAVQNERDR--------------ISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAM 284
            ||..|.:|..||:              :....||...|:....||....:|...|...|  |:..
 Worm    63 GMTPEKIQLTRDKHLNRTIKLEGPCSSLDTPITSRQTPNLYCVLSNWHELKMTREEMNS--GSLN 125

  Fly   285 EPNINE-------DLS------NKQFASINDVCESMKQQLL------------TLVEWAKQIPAF 324
            ..||.|       ||.      :|.|.:: :|.|...:|.|            .::|:.:....|
 Worm   126 NCNIFELTSFVLRDLELTWRMVSKAFPTV-EVLEDRDRQALLRNFVPKLWQIEPILEYRECAEKF 189

  Fly   325 NELQLDDQVALLRAHAGEHLLLGL------SRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDIS 383
            :.|:.:|.         |:||:|.      ..:.|...::  :||            ..|..|.
 Worm   190 DNLEEEDY---------ENLLVGFYGGTFPEGKEMSKSEI--VSN------------FRPYWDY- 230

  Fly   384 RIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEP--HRIKSLRHQILNNLEDYISD 446
                 ...:::..:..:|:::.|:..|..|.|||.....:::.  ...:.::..||..|.:|..|
 Worm   231 -----YYTKMILPISSMGLEELEYMAIVWLAFFDNGYSNISDNCLEMCRDIQKVILKELRNYQID 290

  Fly   447 RQYESRGRFGEILLILPVLQSITWQMIEQI 476
            |.:. ..||...|..|.:::....:.:|::
 Worm   291 RNFH-ENRFFVALEALQIIERGEKKFMEEM 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/74 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	47/246 (19%)
nhr-112	NP_001024286.1	ZnF_C4	2..67	CDD:197701	25/67 (37%)
		HOLI	138..310	CDD:214658	38/202 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910