Protein Alignment Hnf4 and nhr-193

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_507131.1
• Gene: nhr-193 / 180098
• WormBaseID: WBGene00010215
• Length: 384
• Species: Caenorhabditis elegans
• Alignment Length: 407
• Identity: 93/407 - (22%)
• Similarity: 150/407 - (36%)
• Gaps: 107/407 - (26%)

  Fly   168 TVCAICGDRAT-GKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCF 231
            |.|.|||.:.| |.|:|...|..|..||||  |...:|   ....|..:......|:.|||::||
 Worm     2 TNCLICGAKNTRGNHFGVRCCRACAVFFRR--RAGTKY---LRLKCSSENCGNRFCKPCRLKRCF 61

  Fly   232 KAGMKKEAVQNERDRI-----------------------------SCRRTSNDDPDPGNGLSVIS 267
            .|||..|..|:.||.|                             |.|:|..|       |:|:
 Worm    62 AAGMTIEHFQHNRDLIKSTIVPKIPRSFANVVGRPSFVIFCVPQESYRKTFVD-------LNVL- 118

  Fly   268 LVKA--------ENE---SRQSKAGAAMEPNINEDLSNKQFASIN--DVCESMKQQLLTLVEWAK 319
            :.||        ||.   |.|.|..||.. |...|.:.:.|..::  ::....:...|...:|..
 Worm   119 IEKAGEIFEKGPENPYIGSTQLKKLAAAS-NFTMDWNRRSFEPLSHGEMSYFWEFYFLRTAKWLT 182

  Fly   320 QIPAFNELQLDDQVALLRA--HAGEHL-LLGLSRRSMHLK----------------------DVL 359
            ....|.::..|..:.||.:  |....| .|..:.|:..||                      |..
 Worm   183 YFEEFKKIPRDLMIKLLLSFWHVFSRLDKLITTARARKLKVCSQQTWAMSNGFILDFDKTKVDFW 247

  Fly   360 LLSNNCVITRHCPDPLVSPNLD----ISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNA 420
            .|||             .|..|    ::.:.|..:...|..::::.:.|.||..:.|.:.|....
 Worm   248 KLSN-------------YPAKDLFYFLNSMAALDLQPQVQELQELEVSDVEFNFMLAQLTFSYAG 299

  Fly   421 KGL-NEPHRIKSLRHQILNN--LEDYISD---RQYESRGRFGEILLILPVLQSITWQMIEQIQFA 479
            |.| .:..:|.....::|:|  .|.|:.:   ::|.  ||..:|:.|...:|:..|....:.:.|
 Worm   300 KRLQGDILKICEKFQEVLSNDLHEHYVKELGMQRYS--GRLSKIMKINNAIQNDIWSNRPRGELA 362

  Fly   480 KIFGVAHIDSLLQEMLL 496
            .:|.:.::.....||.:
 Worm   363 AVFNIFNVKFSHPEMFI 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/75 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	54/277 (19%)
nhr-193	NP_507131.1	ZnF_C4	3..68	CDD:197701	26/69 (38%)
		Hormone_recep	152..358	CDD:278530	41/220 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910