Protein Alignment Hnf4 and nhr-63

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_741645.3
• Gene: nhr-63 / 180068
• WormBaseID: WBGene00003653
• Length: 363
• Species: Caenorhabditis elegans
• Alignment Length: 368
• Identity: 89/368 - (24%)
• Similarity: 148/368 - (40%)
• Gaps: 69/368 - (18%)

  Fly   168 TVCAICGDRATGKHYGASSCDGCKGFFRRSVR-KNHQYTCRFARNCVVDKDKRNQCRYCRLRKCF 231
            |.|.:||......|:|..||..|..||||... |....:|    .|.:.....:.||.||::|||
 Worm     4 TSCHVCGAPEVEPHFGGVSCRACAAFFRRYFHSKKSVISC----TCQIRYQNSHPCRECRIQKCF 64

  Fly   232 KAGMKKEAVQNERDR-------------ISCRRTSNDDPD-PGNGL---------SVISLVKAEN 273
            :|||..|.||.:|::             :|...:|...|. |.:.|         |.||.:.:..
 Worm    65 EAGMNPEKVQVKREKHPKKLKMELAHASLSSASSSQSPPSLPISPLPYHIVSRNNSTISYIVSTW 129

  Fly   274 ESRQSKAGAAMEPNINEDLSNKQFASIN--DVCESMK---QQLLTLVEWAKQIPAFNELQLDDQV 333
            ...|.|...         |..|:|..:.  :.|.:.|   :.:..:.|:.  .|....|...|:.
 Worm   130 GEVQDKRSV---------LYKKRFDDLTYYEACVASKIDSEIMWNVCEYI--FPQIQSLSNLDKN 183

  Fly   334 ALLRAHAGEHLLLGLS---RRSMHL-KDVLLLSN--NCVITRHC----PDPLVSPNLDISRIGAR 388
            |:||..:.:..||..|   .|:.|| :||:.:.:  :.::..:.    .|..:||. :|.|:...
 Worm   184 AVLRNFSPKWSLLASSIDFERNCHLYEDVVTVDDYLDMIVKFYSGSMYGDNKISPK-EILRVFEP 247

  Fly   389 IID----ELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEP-----HRIKSLRHQILNNLEDYI 444
            .:.    .||..|.....:..|:..:..|:.||.....::..     |.||::   ||..|.||.
 Worm   248 FLTYYGVVLVLPMNAKMFNSIEYMALAMLLLFDGAHANISADCSKMCHDIKNV---ILRELRDYY 309

  Fly   445 SDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHI 487
            .|...:.. ||.|.:..:..::....:.||::...::..| ||
 Worm   310 IDNGVDEM-RFFETIDTVNHVEKGESKFIEELLACELHNV-HI 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/75 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	54/248 (22%)
nhr-63	NP_741645.3	ZnF_C4	6..71	CDD:197701	25/68 (37%)
		HOLI	171..331	CDD:214658	38/164 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910