Protein Alignment Hnf4 and nhr-50

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_507015.3
• Gene: nhr-50 / 180067
• WormBaseID: WBGene00003640
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 384
• Identity: 83/384 - (21%)
• Similarity: 145/384 - (37%)
• Gaps: 88/384 - (22%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVR-KNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKA 233
            |.:||......|:||.||..|..||||... |.....|    ||.|.....:.||.||::||...
 Worm     3 CQVCGCSDVEPHFGALSCRACAAFFRRYFHSKKVVGQC----NCAVRFRNSHPCRECRIKKCLSI 63

  Fly   234 GMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFA 298
            ||..|.||.:|:|...::  |..|.....|:               :.::..|::  .:|.....
 Worm    64 GMNPEKVQEKRERHPPKK--NKPPSISEALT---------------SSSSTPPSL--PISQLPSR 109

  Fly   299 SINDVCESMKQQLLTLVEWAKQIPAFNEL---------------QLDDQVALLRAHAGEHLLLGL 348
            .|...|.|:   .||...|.|..|..|.:               :::|.:.:.|  ..|.|...|
 Worm   110 IIPRDCSSI---TLTAFNWQKCQPKRNYMTRTLDETNYYQLSCFKIEDCMMIWR--IVEDLFPSL 169

  Fly   349 SRRSMHL-KDVLLLS------------------------NNC---------VITRHCPDPLVSPN 379
            :.....| |:.||.:                        ||.         ..|...|:....|.
 Worm   170 TWNLRKLDKEALLRNFLPKWSVLTAAIDMEVKVQRYSKVNNTEEFKRMIVDFFTYSMPEKFKMPP 234

  Fly   380 LDISRI-GARI---IDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNE--PHRIKSLRHQILN 438
            .||.:: |..|   :.:::..:.:.|:|..||..:..::.||.....::.  ....:::|:.|..
 Worm   235 EDILKVFGPMIVYYVTKIILPIHEKGLDQPEFMALALIILFDGAYSNISVECSEMCRTIRNLIFR 299

  Fly   439 NLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGV-AHID--SLLQEM 494
            .|::|.:|:.::.. :|.:.:..|.:::....:..|::....:..| .|.|  .||.|:
 Worm   300 ELKNYQTDKNFDEI-QFADTVDTLNIVEKGEKKFYEELLICDMHNVHLHEDYRLLLNEL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	29/75 (39%)
		NR_LBD_HNF4_like	264..494	CDD:132729	48/287 (17%)
nhr-50	NP_507015.3	ZnF_C4	3..68	CDD:197701	26/68 (38%)
		HOLI	156..327	CDD:214658	30/173 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910