Protein Alignment Hnf4 and nhr-53

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_741644.1
• Gene: nhr-53 / 180053
• WormBaseID: WBGene00003643
• Length: 364
• Species: Caenorhabditis elegans
• Alignment Length: 397
• Identity: 89/397 - (22%)
• Similarity: 161/397 - (40%)
• Gaps: 77/397 - (19%)

  Fly   137 MFSPN---NNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSV 198
            |.||.   ||...|.|              |..|:.|.||.:.|.|.|:||::|..|..||||:|
 Worm     1 MPSPTHLLNNFESSSS--------------QGPPSYCLICCEVADGHHFGAAACRACAAFFRRTV 51

  Fly   199 RKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCR---RTSNDDPDPG 260
            :.|..:.|.....|.:..:.||.||.||..||.:.||::.:||.:||::..|   .|:.::|
 Worm    52 QLNKVHDCPKNGQCFILSNVRNMCRACRYEKCLEVGMQRSSVQQKRDQLGRRDGLPTNREEP--- 113

  Fly   261 NGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQ------FASINDVCESMKQQLLTLVEW-A 318
                |:..::...|....         :.:.:.|:|      ..|.|::....:.::..:.:: .
 Worm   114 ----VLDTMRRAYEKLLV---------VRKKVHNRQENQLPRAISFNELQVVYQNEMTVIYQFLC 165

  Fly   319 KQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKD---VLLLSNNCVITRHCPDPLVSPNL 380
            :..|.::||..|.:.:|.:.......||..|......|.   :|:.|.:.|...|......:.:.
 Worm   166 EAFPEYSELLPDTKRSLFKNFFLPFTLLESSYYGYLTKQENVMLIPSGDYVDLAHLESYFNNNHH 230

  Fly   381 DISRIGA--------RIIDELVTV-MKDVGIDDTEFACIKALVFF------DPNAKGLNEPH-RI 429
            ..|:...        |::...:|| :....:|..||..:.|::.:      :.:.|.:.|.. :|
 Worm   231 TFSQKDTISMFAQQFRMLHTSITVPLSAENVDVNEFLALAAIILWESDLEVEADRKNVQEEAVKI 295

  Fly   430 KS-------LRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHI 487
            ||       ..:|.:|...|...        |.|.:|.|||.:|..:.:..|.::...:..:..:
 Worm   296 KSAIIKDLLFHYQSINVYADVAM--------RLGAVLSILPSIQRASHRFHEYMEIKNLLNLYAL 352

  Fly   488 DSLLQEM 494
            ...|.:|
 Worm   353 PKNLYDM 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/74 (41%)
		NR_LBD_HNF4_like	264..494	CDD:132729	44/262 (17%)
nhr-53	NP_741644.1	NR_DBD_like	23..98	CDD:295381	30/74 (41%)
		Hormone_recep	134..340	CDD:278530	40/213 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910