Protein Alignment Hnf4 and nhr-57

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504153.1
• Gene: nhr-57 / 178813
• WormBaseID: WBGene00003647
• Length: 374
• Species: Caenorhabditis elegans
• Alignment Length: 369
• Identity: 71/369 - (19%)
• Similarity: 140/369 - (37%)
• Gaps: 76/369 - (20%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKN--HQYTCRFARNCVVDKDKRNQCRYCRLRKCFK 232
            |::|.....|.|:||.:|..|..||||:...|  .::.||....||:....|:.|:.||..||..
 Worm    10 CSVCHQLGDGYHFGAIACKACAAFFRRTTSMNLAPKFVCRKKNECVIKMSSRDSCKSCRYAKCLH 74

  Fly   233 AGMKKEAVQNERDRISCRRTSNDDPDPG--------------NGLSVISLVKAENESRQSKAGAA 283
            .||..|.||      :.::.:.....||              |. .::||...:.:.........
 Worm    75 VGMNPEVVQ------AIQQAAKQANSPGIESLPSCSSSPASCNS-PILSLELGDYDQMTPTLCGV 132

  Fly   284 MEPNINEDLSNKQF-----------ASINDVCESMKQQLLTLVEWAK-QIPAFNELQLDDQVALL 336
            ||.  .:.|..|::           .:..:.|:.....:....|:.: ..|.|.|:...::..:.
 Worm   133 MES--YQKLYKKRYDLHAPKLTPRATNYGEFCKIYSNDVYLQFEFLEGSFPQFKEMGGFEKKHVF 195

  Fly   337 RAHAGEHLLLGLSRRS-MHLKDVLLLSNNCVITR-------HCPDPL-----------VSPNLDI 382
            :......|:|.:..|| ....|.::|:|...|..       :.|:.|           ..||.|.
 Worm   196 KYFFVSFLILEMGYRSYQEGTDAIVLANGDFIDTMNLDEFYYDPESLEKCKPTDAMKMYRPNFDQ 260

  Fly   383 SRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPH--RIKSLRHQILNNLEDYIS 445
            .:   |.:.:.::..|   :...||..:.:|..::.:..|..:.:  ..:.:|..::.:|:.:
 Worm   261 MK---RNVFQPLSHQK---LSLIEFLALVSLCTWNESLDGQPDCYYPSCRPVRQSVIADLKAF-- 317

  Fly   446 DRQYESRG-------RFGEILLILPVLQSITWQMIEQIQFAKIF 482
               ||...       |...:|::||.|:......::.::..::|
 Worm   318 ---YEKDSPDVDPAYRLSGLLMLLPALERSVELFLQTMEVKRLF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/76 (37%)
		NR_LBD_HNF4_like	264..494	CDD:132729	40/259 (15%)
nhr-57	NP_504153.1	ZnF_C4	10..80	CDD:197701	25/69 (36%)
		Hormone_recep	153..350	CDD:278530	33/207 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910