Protein Alignment Hnf4 and nhr-18

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_503608.2
• Gene: nhr-18 / 178702
• WormBaseID: WBGene00003617
• Length: 394
• Species: Caenorhabditis elegans
• Alignment Length: 421
• Identity: 97/421 - (23%)
• Similarity: 145/421 - (34%)
• Gaps: 137/421 - (32%)

  Fly   170 CAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARN--CVVDKDKRNQCRYCRLRKCFK 232
            |.:|||:.:|:|:|..||..|..||||:...|.:.  |...|  |....:.:..|:.|||:||..
 Worm    11 CEVCGDKTSGRHFGVMSCRACAAFFRRAATWNLEK--RICPNGTCHTSVNGKFNCKQCRLKKCLD 73

  Fly   233 AGMKKEAVQNERDRISCRRTSND--------------DPDPGNGL----SVISLVKAENESRQSK 279
            .||.....|.:||.|||...|..              :||..:.|    .|..||....:..|..
 Worm    74 VGMDTRRFQTDRDLISCSAISQSLATFLGRPEFILCCEPDRASVLKTTIDVTRLVNIARDMLQKP 138

  Fly   280 AGAAMEPNINEDL-----------SNKQFASIN-----DVCESMKQQLLTLVEWAKQIPAFNELQ 328
            ....:..|..|.|           |||:...|.     :..:|.:|..|.:|||......|.||.
 Worm   139 TNHVLPSNSLEQLATTLDNMRCVESNKEVKFIEKYGKVETLKSWEQGFLRVVEWFSNFSEFRELN 203

  Fly   329 LDDQVALLR---------------AHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSP 378
            ...::.:::               |:...:.:||        |..|::.|...:.
 Worm   204 ERLKLEIVKSCWFSWTRLDKLSETANKQINKMLG--------KSQLMVGNGACMN---------- 250

  Fly   379 NLDISRIGARIIDELVTVMKDVGID---DTEFACIKALVFFD-PNAK-----------GLNEPHR 428
                              |.:..||   .|.::..:...||. ||.|           .|| |..
 Worm   251 ------------------MNNFEIDLSWCTNYSLEQLKYFFQTPNGKKNFQQSIQDMIDLN-PSS 296

  Fly   429 IK--------SLRH-----------------QI-LNNLEDYISDR----QYESRGRFGEILLILP 463
            |:        ||.|                 |: .|||..|..::    .|.|  |..:::.|..
 Worm   297 IEVSYMLLHLSLEHAGKRLHGDALDATENLVQVQANNLHKYYVEKLKLANYSS--RLTQLMRITR 359

  Fly   464 VLQSITWQMIEQIQFAKIFGVAHIDSLLQEM 494
            .|::.....||:.|.|.:|.:..||....||
 Worm   360 TLEADIRIRIEKKQIADVFNIMKIDFSHPEM 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	27/76 (36%)
		NR_LBD_HNF4_like	264..494	CDD:132729	59/305 (19%)
nhr-18	NP_503608.2	NR_DBD_like	11..86	CDD:295381	27/76 (36%)
		Hormone_recep	163..371	CDD:278530	46/246 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910