Protein Alignment Hnf4 and nhr-106

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_503219.1
• Gene: nhr-106 / 178571
• WormBaseID: WBGene00003696
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 88/381 - (23%)
• Similarity: 149/381 - (39%)
• Gaps: 57/381 - (14%)

  Fly   168 TVCAICGDRATGKHYGASSCDGCKGFFRRSVR-KNHQYTCRFARNCVVDKDKRNQCRYCRLRKCF 231
            |.|.||...|.|.|:||.:|.||..||||:|. |.::.:|:::.||.....|..||:.||:|||.
 Worm     3 TTCEICEVPAHGIHFGAITCRGCAAFFRRAVNTKTNRKSCKYSSNCTNFTGKFPQCKSCRMRKCI 67

  Fly   232 KAGMKKEAVQ-----NERDRISCRR------TSNDDPDPGNGLSVISLVKAENESRQSKAGAAM- 284
            |.||..|.|:     ::...|...|      |:|.| ...|.:.|.:|:....|..:......:
 Worm    68 KMGMMPEKVKVMQPISQSLEIFVSRPNLILFTNNYD-KTRNYIDVSNLITRGLEILKQGFPTPLG 131

  Fly   285 --EPNINEDLSNKQFAS----INDVCESMKQQL------LTLVEWAKQIPAFNELQLDDQVALLR 337
              :.|:....|..:|::    |.||.......:      ::..:|..::..|..|.:..|:.||:
 Worm   132 IGKTNLERMASGVEFSTAESKIVDVVTGKSVSMVWEFDFISTAKWLTRLQDFCTLPMRIQMQLLQ 196

  Fly   338 A--HAGEHL---LLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDEL---- 393
            .  |....:   :.....|..|...    ||...:.......|.:..||:|.:.....:|:
 Worm   197 TIWHVWSRMYKVVKSSELRKKHADS----SNLFQVLDQFHVNLGTTKLDVSWLTTYSYEEIKYFL 257

  Fly   394 ------------VTVMKDVGIDDTEFACIKALVFFD--PNAKGLNEPHRIKSLRHQIL-NNLEDY 443
                        :|....:.:.|.|...:.|...|.  .|.....|...:.:...:|| |:|..|
 Worm   258 YGIDDDIYLQSAITAASKLELTDVELTYMAAQTCFQYAQNRFAGTEIAEVCAKFQEILANDLHTY 322

  Fly   444 IS-DRQYESR--GRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLL 496
            .: |.:..|.  |:..::|..:..:|.......|:...|:.|.:...|....||.:
 Worm   323 YTKDHKRTSNYAGKLSQMLKCVQEIQKSIRTTRERTTIARTFDIYITDFSNPEMFI 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	33/80 (41%)
		NR_LBD_HNF4_like	264..494	CDD:132729	46/269 (17%)
nhr-106	NP_503219.1	ZnF_C4	4..74	CDD:197701	31/69 (45%)
		Hormone_recep	150..357	CDD:278530	36/210 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910