Protein Alignment Hnf4 and nhr-55

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_503215.2
• Gene: nhr-55 / 178570
• WormBaseID: WBGene00003645
• Length: 424
• Species: Caenorhabditis elegans
• Alignment Length: 430
• Identity: 93/430 - (21%)
• Similarity: 159/430 - (36%)
• Gaps: 94/430 - (21%)

  Fly   137 MFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKN 201
            |.||:::.|...|.::.|...|      .||..|.:||.::.|||:||.:|..|..||||....|
 Worm     1 MNSPSSSSSFCSSSSSPSSLVL------YSPDTCQVCGQKSHGKHFGAVTCRACAAFFRRCGSAN 59

  Fly   202 HQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRISCRRTS-------NDDP-- 257
            :...||...||...|:....|:.|||:||...||..|..|.:||..|.::..       |..|
 Worm    60 NFKPCRRNMNCEFLKNGWFNCKPCRLKKCQDVGMTIENFQFDRDSFSPKKAKIALENFHNQVPFS 124

  Fly   258 -DPGNGLSVISLVKAENE------------------SRQSKAGAAM---EPNINEDLS------- 293
             ....|.|.:.::.|..|                  |...|.|..:   .||..|.|:
 Worm   125 IATFTGRSNLIVISAPTEEECIPKCYIDVQFLIDKLSNVLKEGPEVPLHTPNALEKLALGLQIIR 189

  Fly   294 --NKQFASINDVCES-----MKQQLLTLVEWAKQIPAFNELQLDDQVALLR------AHAGEHLL 345
              .::...|..:.:.     .:..::.:.:|......|.:|....:..:|:      :......|
 Worm   190 GRKRELKLITKLGKEETLGLWQDDMMKVAKWLTYFDDFQQLSHRMRSEMLKGMWKVWSRLETLAL 254

  Fly   346 LGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPN-----LDISRIGARIIDELVTVMKDVGIDDT 405
            ..:.||       |::....:|..|.....|..:     :|||......:::| ....|..:||.
 Worm   255 TAMGRR-------LMICQKDMIMTHTEKEQVMAHPKQIEVDISWCSRYTLEQL-RFFADSDLDDR 311

  Fly   406 EFACIKALVFFDPNAKGLN-----------------EPHRI-KSLRHQILNNLEDYISDR----Q 448
            ....|:|::...|....|:                 |...| :..:..:.|:|.||..:|    |
 Worm   312 NEQVIQAMMELQPTDVELSYMMCQACLHYAGKRYQGEVLEIAERFQETLSNHLHDYYVNRMNMPQ 376

  Fly   449 YESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHID 488
            |..  |...::.|...:|...::...:...|::|.|.:::
 Worm   377 YSM--RVANLMKINNHIQLDIYRGRVKYDLARVFDVFYLE 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	30/74 (41%)
		NR_LBD_HNF4_like	264..494	CDD:132729	48/293 (16%)
nhr-55	NP_503215.2	ZnF_C4	27..96	CDD:197701	28/68 (41%)
		Hormone_recep	194..401	CDD:278530	35/216 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910