Protein Alignment Hnf4 and nhr-99

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_503214.1
• Gene: nhr-99 / 178569
• WormBaseID: WBGene00003689
• Length: 418
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 90/444 - (20%)
• Similarity: 159/444 - (35%)
• Gaps: 134/444 - (30%)

  Fly   139 SPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQ 203
            ||:::||...|....:          :|...|.||...:.|||:||.:|..|..||||..|..:.
 Worm     5 SPDSSLSSLDSPLVPT----------RSMRTCEICDKPSHGKHFGAVTCRACAMFFRRFGRCKNM 59

  Fly   204 YTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERDRIS-------------------- 248
            ..|....||...|:....|:.|||:||:..||..:..|:...:::
 Worm    60 KPCEMNNNCQFPKNGYFNCKKCRLQKCWDVGMTTDTFQSVISKLAKPTLQVKIPETIGTLIGLPN 124

  Fly   249 ---------------CR----------------RTSNDDPDPGNGLSVISLVKAENESRQSKAGA 282
                           |:                ||..:.|           :.|:|...:...|.
 Worm   125 LIIFNAPEFEAPSSICKNFIDVRYLVSQGEQILRTGLETP-----------IIAQNSLEKMALGL 178

  Fly   283 AMEPNINEDLSNKQFASINDVCESMKQQLLTL-----VEWAKQIPAFNEL-QLDD--QVALLRAH 339
                   |.:...:...||::....::::.||     ::.||.:..|:|. ||.|  |:..|::
 Worm   179 -------EYIRKMRNPKINNIRRIGQKEVFTLWQDDFLKTAKWLTYFSEFQQLPDGLQMKFLKS- 235

  Fly   340 AGEHLLLGLSRRSMHLKDVLL------LSNNCVITRHCPDPLVSPNLDISRIGARI--------- 389
                 :..|..|...|...::      .|:|.|:.:.....:|   .||.:|...:
 Worm   236 -----IWKLWSRFERLVTTMIGRRNSACSSNMVLIKLDDTQVV---FDIKKIDVDVSWQSRYNVE 292

  Fly   390 -------------IDELVTVMKDVGIDDTEFA---CIKALVFFDPNAKG--LNEPHRIKSLRHQI 436
                         .||::..|.|:...:.|.:   |...|.......:|  |....|::|   .|
 Worm   293 QLKLFGYSYLDEKYDEIIQEMIDLDPTNVELSFMVCQLCLHHIGKKFQGDILKVAERLQS---SI 354

  Fly   437 LNNLEDYISDRQYESR--GRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHID 488
            .|||.||..:::...|  ||..:::.|...:|...::...:....::|.|.|::
 Worm   355 ANNLHDYYVNKEKRPRYSGRIAKMMKINNYIQKGIYERRVKADLMRVFDVFHVE 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	28/74 (38%)
		NR_LBD_HNF4_like	264..494	CDD:132729	52/268 (19%)
nhr-99	NP_503214.1	ZnF_C4	25..94	CDD:197701	27/68 (40%)
		Hormone_recep	185..395	CDD:278530	45/221 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910