Protein Alignment Hnf4 and nhr-100

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_501731.1
• Gene: nhr-100 / 177806
• WormBaseID: WBGene00003690
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 370
• Identity: 93/370 - (25%)
• Similarity: 157/370 - (42%)
• Gaps: 83/370 - (22%)

  Fly   166 SPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKC 230
            |.|.|.:|||....:||||.||:|||||||||:.:...|.|.|...|:::...||:||.|||::|
 Worm    20 SDTSCLVCGDPHGKRHYGAMSCNGCKGFFRRSIWEKRTYKCSFNNECIIEFKYRNRCRACRLKRC 84

  Fly   231 FKAGMKKEAVQNERDRISCRRTSNDDPDPGNGLSVISLVKAENESRQSKAGAAMEPNI------- 288
            ...||...||::||.|..  :|..|    |:....|....|::|....:....::|:|
 Worm    85 LHVGMDANAVRSERTRKI--KTEID----GDVKLEIKEEPADSEDADDECPLDIKPDIAMAWQTK 143

  Fly   289 --------NED----------------LSNKQFASIND---VC-------ESMKQQLLTL----- 314
                    .||                :.::...:|.|   ||       .|..:.|:|:
 Worm   144 EIIAHMLYEEDRVLNWEEPYNKLRYYTMDSEVLQAIKDPSQVCARTKINWNSHSRPLITIEALRF 208

  Fly   315 ---------VEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLK-DVLLLSNNCVITR 369
                     ::|.:.:|.:..|..||:..|::........|..:.:|...: |.::..:.....|
 Worm   209 NWCRTFTLTIDWFETLPEYRALIDDDKELLVKFSLMPVGWLWYAYKSYEYRCDGIVFVDGSWFPR 273

  Fly   370 H-------CPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPH 427
            .       ||..:    |...||....:.::|..||::.:|:||...:||:....|:.:.....:
 Worm   274 DKTIQQQVCPTCV----LYYGRITESFMADVVNSMKELEMDETEMVLLKAICHLQPDYRLTRRGN 334

  Fly   428 RIKSL-RHQILNNLEDYISDRQYESRG------RFGEILLILPVL 465
            .:.|. |.:....|.:||   :.:|.|      |..:::.||||:
 Worm   335 DVISTGREKYKRALCEYI---RMKSNGFMDASFRLCKLMQILPVV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	36/74 (49%)
		NR_LBD_HNF4_like	264..494	CDD:132729	50/272 (18%)
nhr-100	NP_501731.1	NR_DBD_HNF4A	24..98	CDD:143518	35/73 (48%)
		HOLI	210..376	CDD:214658	35/172 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010