Protein Alignment Hnf4 and nhr-31

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_741456.1
• Gene: nhr-31 / 177601
• WormBaseID: WBGene00003625
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 136/522 - (26%)
• Similarity: 230/522 - (44%)
• Gaps: 97/522 - (18%)

  Fly   145 SGSGSGT------NSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQ 203
            |.||..|      :..|..:.....|...:|||:|||.....|||..:|.||||||||::...::
 Worm    51 SSSGPATSYIIRPSDKQPTVSSGGSQNGDSVCAVCGDGIAKLHYGVLACYGCKGFFRRTLTGKYR 115

  Fly   204 YTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNERD--------RISCRRTSND----- 255
            |.|||:.||:|||.:||.|||||.::|.:|||..:||:.:||        ||..::...:
 Worm   116 YACRFSNNCIVDKFQRNSCRYCRFQRCIQAGMDPKAVRPDRDQTGKQKVPRIKKKQIDEELLNHM 180

  Fly   256 ----DPDPGNGLSVIS-------------LVKAENE-SRQSKAGAAMEPNINEDLSNK------- 295
                ..|....|.|.:             :||.:|. |.|:.|......::.|...:|
 Worm   181 MRLQGDDWSRKLPVETRILLMQLMSIEDKVVKGDNNMSAQNTAKDPKSISLREMFESKPALDGRR 245

  Fly   296 --------QFASINDVCESMKQQLLTLVEWAKQIPAF-NELQLDDQVALLRAHAGEHLLLGLS-R 350
                    :.|...::.....::.:..|:|...:... :.:..:|:|||:::......:...| |
 Worm   246 MEIGYEPFRMARTEELGVIAHRRAIAAVDWVDSLTEIADAVDTEDKVALVKSCYSPLTIFNFSAR 310

  Fly   351 RSMHLK--DVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKAL 413
            .:.:.|  |:|.|.::..:.|..|......|...:.:..|.::|||..::.:.:.:.|...:||:
 Worm   311 TAQNTKNPDILCLCSHSFVPRRLPPEFNETNHLSNFLIDRTLNELVAPLRKLNLKEEEIVPLKAI 375

  Fly   414 VFFDPNAKGLNE--PHRIKSLRHQILNNLEDYISDRQ--YESRGRFGEILLILPVLQSITWQMIE 474
            :..:||||||:|  .|.|..||.::.:.|...:.:..  |.:..|||.:||:||.:.:::..|.|
 Worm   376 IILNPNAKGLSEHARHAISELRDKVQDMLFQIVKELHPIYSASSRFGNLLLLLPTITTLSGLMSE 440

  Fly   475 QIQFAK-IFGVAHIDSLLQEML-------------LGGELADNPL-----PLSPPNQSN------ 514
            .:.|.: :.|.|..|:||.||.             :...|.:||.     .:|||....
 Worm   441 NMHFCQALGGRASGDNLLAEMFGDRTFDDQLISSSISPPLFENPAEICLESISPPMSDRRFVRRV 505

  Fly   515 DYQSPTHTGNMEGG------NQVNSSLDS------LATSGGPGSHSLDLEVQHIQALIEANSADD 567
            |..:.|:...:..|      |..:|.|::      |:||..|.....|...|:..:|.|.|..::
 Worm   506 DVATQTNDDLLSSGPYLPHSNSCSSMLNAGYSPPMLSTSPFPLLDDNDSAFQNDISLTELNGCEE 570

  Fly   568 SF 569
            .|
 Worm   571 FF 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	39/74 (53%)
		NR_LBD_HNF4_like	264..494	CDD:132729	60/267 (22%)
nhr-31	NP_741456.1	NR_DBD_HNF4A	82..157	CDD:143518	39/74 (53%)
		NR_LBD	259..423	CDD:132726	37/163 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910