Protein Alignment Hnf4 and nhr-20

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_497849.1
• Gene: nhr-20 / 175546
• WormBaseID: WBGene00003619
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 445
• Identity: 96/445 - (21%)
• Similarity: 173/445 - (38%)
• Gaps: 127/445 - (28%)

  Fly   170 CAICGDRATGK-HYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKA 233
            |.:|.....|. |:|::||..|..||||:|..|.|:.|:..:|||:..:.|..||.||..||.||
 Worm    19 CLVCEHPDGGSAHFGSTSCLACAAFFRRTVSLNIQFQCKKDKNCVIFHELRMICRACRFDKCVKA 83

  Fly   234 GMKKEAVQNER---------------DRI-----SCR-RTSNDDPDPGNGLSV------------ 265
            ||::|.||..|               |:|     .|: ..|.|..|..:.||:
 Worm    84 GMRRECVQKRRSNKKIPKKHMNMLREDQIKMEYDECKFECSGDQTDDNSPLSIEKKSPPGLLPND 148

  Fly   266 ---ISLVKAENESRQSKAGAA---MEPNINEDLSNKQFASIN----------------------- 301
               ::..|.:.....|.:|.:   :|.:.:..|:..:..|:|
 Worm   149 SPMMADFKFDPSDIPSTSGGSTQRLERSPSPKLAESKILSMNGEELLRFYVDQLKNSMDRRRMIF 213

  Fly   302 -----------------DVCE----SMKQQL-------LTLVEWAKQIPAFNELQLDDQVALLRA 338
                             |..|    |:|:|.       |...::.|..|.|:.|...::....|:
 Worm   214 TDTALLAVIDDRGDVPFDATEPPPHSLKRQYESQRFDNLLAFDFCKCCPGFDFLSRVEKAIFFRS 278

  Fly   339 HAGEHLLLGLSRRSMH------LKDVLLLSNNCVITRH------------CPDPLVSPNLDISRI 385
            .:..:.||.::..::.      .:.||:.::..|.|.:            |...  ...|.:..:
 Worm   279 CSLAYCLLDIAWITVQAYPEEAAEPVLMYTDGSVCTVNNLSYGWDDEEDICAHD--KKKLFLGFL 341

  Fly   386 GARIIDELVTVMKDVGIDDTEFACIKALVF-------FDPNAKGLNEPHRIKSLRHQILNNLEDY 443
            | |..|.:...::::.:...|||.:|||..       |.|:.|.:.:.|     ...:||.|.:|
 Worm   342 G-RFNDAICRPIRNLKMTHVEFAALKALCIWKLGYCEFTPSMKVIGKEH-----EEALLNGLHNY 400

  Fly   444 ISD---RQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEML 495
            ..|   ...|:..|.|.::|::..:..:...::|..:.|::|.:..:|:|.:.:|
 Worm   401 YDDLYGNPDETGMRIGNLILLMGTVFEMNQLIMETYKSAELFELFKLDALSKSLL 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	34/90 (38%)
		NR_LBD_HNF4_like	264..494	CDD:132729	54/326 (17%)
nhr-20	NP_497849.1	ZnF_C4	18..88	CDD:197701	30/68 (44%)
		NR_LBD	244..428	CDD:132726	36/191 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910