Protein Alignment Hnf4 and nhr-80

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_871630.1
• Gene: nhr-80 / 175167
• WormBaseID: WBGene00003670
• Length: 504
• Species: Caenorhabditis elegans
• Alignment Length: 466
• Identity: 106/466 - (22%)
• Similarity: 154/466 - (33%)
• Gaps: 164/466 - (35%)

  Fly   166 SPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFAR-NCVVDKDKRNQCRYCRLRK 229
            |.|.|.||..:|||.|:.|.||..|..||||:|.....:.|...| :|.|.......||.||.:|
 Worm    26 SSTRCLICSAQATGFHFEAQSCSACAAFFRRTVALTKSFKCITGRDDCNVHYSMHQICRSCRHKK 90

  Fly   230 CFKAGMKKEAVQNERDRISCRRT-------------SNDDPDPGNGLS-VISLVKAENESRQSKA 280
            |...|||...||.::..|...|.             :|..|...:... |:..||......|
 Worm    91 CLSNGMKPGGVQPKKPNIETGRAFFTKSGLKRNKKFANVSPQTADEQKLVVEGVKVPKIEVQ--- 152

  Fly   281 GAAMEPNINEDL-----------------SNKQFASI---------------------------- 300
                |||..|||                 |:..|::.
 Worm   153 ----EPNSLEDLEQDNEFVIKTPTPRKISSSTSFSASTTTNYSTPGPSPMAPCSAGPDVLTLFIR 213

  Fly   301 ------------------------NDVCESMKQQLLTLV----------------EWAKQIPAFN 325
                                    |..|...|:.:..||                ||.:..|...
 Worm   214 EEMKLGERRRLLFSERAVGTLLGQNKHCPYKKEDIKPLVFHDFRLTIKTHIMLVYEWLQTWPELQ 278

  Fly   326 ELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPN----------- 379
            ||...|:::|||.....|.||..|..|..:.:              ||.|:..|
 Worm   279 ELDDFDRMSLLRKAVLIHFLLDPSFLSYQIGE--------------PDKLIMQNGGFISTADHHG 329

  Fly   380 ------LDIS---------RIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHR- 428
                  .|||         .|..:|.||::..|:.:.|...||..:|||..|....:.::|..|
 Worm   330 VGWEDETDISGENKRKYYVPIMKQITDEIMPAMEAMKITFEEFVALKALACFQGGFENVSEAKRH 394

  Fly   429 ---------IKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGV 484
                     :.||....|.|.|:.|::       |||.|:|:|..:.:.....::..:...||.:
 Worm   395 LITQQVNRIMTSLHTHYLENSEEKIAE-------RFGTIVLMLSNIFTAGNDFVQNHREIDIFHI 452

  Fly   485 AHIDSLLQEML 495
            ..:|.|:.::|
 Worm   453 WDLDKLVLQLL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	31/75 (41%)
		NR_LBD_HNF4_like	264..494	CDD:132729	68/351 (19%)
nhr-80	NP_871630.1	ZnF_C4	30..98	CDD:197701	28/67 (42%)
		HOLI	261..436	CDD:214658	47/195 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910