Protein Alignment Hnf4 and nhr-61

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001022382.1
• Gene: nhr-61 / 175142
• WormBaseID: WBGene00003651
• Length: 415
• Species: Caenorhabditis elegans
• Alignment Length: 432
• Identity: 97/432 - (22%)
• Similarity: 164/432 - (37%)
• Gaps: 108/432 - (25%)

  Fly   142 NNLSGSGSGTNSSQQQLQQQQQQQSPT---------VCAICGDRATGKHYGASSCDGCKGFFRRS 197
            :::|.|.:.|:||           |||         .||:|||.|.|||||.::|:|||||||||
 Worm     4 DSISSSTASTSSS-----------SPTRGTPIRKSLQCAVCGDVALGKHYGVNACNGCKGFFRRS 57

  Fly   198 VRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQ--------------------- 241
            :.||..|.||....|:|.|::||.||.|||.:|...||...|||
 Worm    58 IWKNRTYACRHGGKCLVAKEQRNACRSCRLTRCLDVGMNPRAVQGDTVEDPEWDEEAMPETLSIS 122

  Fly   242 NERDRISCRRTSN-----------------------DDPD-------PG--------NGLSVISL 268
            .:.|.:..::.|:                       .||:       ||        :...|:|
 Worm   123 TQTDALKVKKKSHTSLFTLDIKKEQIIDNLRAIYARTDPEEFWKLTYPGTYDFRYAFHNTKVVS- 186

  Fly   269 VKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQV 333
                             |......:.::.|::|||....::..:..|:..|.|....::|.||::
 Worm   187 -----------------PRTPLTPTAERIATLNDVVADFRRAFVLFVDILKSIDQLRDVQEDDKM 234

  Fly   334 ALLRAH-AGEHLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPN--------LDISRIGARI 389
            .:.::. |..:..|..:..:....:.:..||.........|...|..        :|.|.:..:.
 Worm   235 KIAKSRFAAFYWWLCSTWSAKAGCNGVCYSNGSYHPASISDMPKSEGKHGVRIEYVDYSGVSQKS 299

  Fly   390 IDELVTVMKDVGIDDTEFACIKALVFF-DPNAKGLNEPHRIKSLRHQILNNLEDYISDRQYESRG 453
            ::.||..::.:.:.|.|......:|.. ||......:..:|.:........|..|......|.:|
 Worm   300 LENLVEPLRRMELSDEERIVGAVMVILADPVPNVSTKTEKILAEARDFYLELLGYCIKLPEEQQG 364

  Fly   454 -RFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEM 494
             |...::|:|..:..:.....:.||.:.:..|..:....||:
 Worm   365 IRVSTMVLLLASIMELVHLTTDNIQLSDVLHVIDLGDWSQEL 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	42/95 (44%)
		NR_LBD_HNF4_like	264..494	CDD:132729	40/240 (17%)
nhr-61	NP_001022382.1	NR_DBD_HNF4A	30..103	CDD:143518	42/72 (58%)
		HOLI	208..380	CDD:214658	29/171 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910