Protein Alignment Hnf4 and nhr-62

DIOPT Version :9

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_492607.1
• Gene: nhr-62 / 172836
• WormBaseID: WBGene00003652
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 472
• Identity: 107/472 - (22%)
• Similarity: 194/472 - (41%)
• Gaps: 113/472 - (23%)

  Fly   134 NNSMFSPNNNLSGSGSGTNSSQQQLQQQQQQQSPTVCAICGDRATGKHYGASSCDGCKGFFRRSV 198
            :.|..|.::..:|.|.|         :::......||.:|||:|.|||||.::|:||||||||||
 Worm    71 HTSTSSAHHTTTGHGRG---------RRKNSTINLVCVVCGDQAFGKHYGVNACNGCKGFFRRSV 126

  Fly   199 RKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNER------------------- 244
            ..|.||.|||...|.:.|:.||.||.|||::||.|||...|||:||
 Worm   127 WHNRQYLCRFEGRCAIAKEHRNVCRACRLKQCFVAGMNPRAVQSERVEREQNGSPNQIEEDDYKD 191

  Fly   245 ----DRISCR-RTSNDDPDPGNGLS---------------------------VISLVKAEN---- 273
                |..|.. :|..|:..|.:..|                           |..:.|.||
 Worm   192 LSSPDTCSVEIQTDVDEQKPSSNNSAPLPSMELEMAKLSEQIVEMHRAVCSYVDPVTKRENFDMK 256

  Fly   274 -ESRQSKAG--------AAMEPNINEDLSNKQFASINDVCESMKQQLLTLVEWAKQIPAFNELQL 329
             |:..:|..        ..:.|....|::.::.|::.||.:..|:..:...:|.:.:|.:|::.:
 Worm   257 METETTKIAFMNAFYNPEMIGPRTPLDITGRRVATVKDVMDEWKRNFVLFSDWLRALPEYNQMSI 321

  Fly   330 DDQVALLRAHAGE-HLLLGLSRRSMHLKDVLLLSNNCVITRHCPDPLVSPNLDISRIGARIIDEL 393
            :||:.|.:...|. |..:..:.......:.:..||.....:. |:....|  |:.....|:.|.|
 Worm   322 EDQIVLAKNRYGTFHWWMCANWTVQAGCEGVCYSNGAYFPKQ-PEAQCIP--DVKGSSGRMYDSL 383

  Fly   394 VTVMKDVGIDDTEFACIKALVFFDPNAKGLNE-----PHRIKSLRHQILNNLEDYISDRQY---- 449
            ...:|::.:|:||...:.|::.|......|.:     ...::.:.::.:..|..:::.::|
 Worm   384 SIPIKELNLDETEIVLMLAVIIFSDEITELADLTPAGKEHVRMVGNRFVRMLHHHVNSKEYGEAM 448

  Fly   450 ----------ESRG--RFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSLLQEMLLGGELAD 502
                      ||:.  |..:::::|....::.:...:.||..::..|...:.|..|:..
 Worm   449 ENGDDTQNSSESQAAVRIAKMMILLSATTNLVYLTSDNIQLMEVLHVVPSEYLCHEVQF------ 507

  Fly   503 NPLPLSPPNQSNDYQSP 519
                     ..|.|::|
 Worm   508 ---------IQNSYETP 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	46/97 (47%)
		NR_LBD_HNF4_like	264..494	CDD:132729	46/291 (16%)
nhr-62	NP_492607.1	NR_DBD_HNF4A	98..173	CDD:143518	45/74 (61%)
		HOLI	299..475	CDD:214658	30/178 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910