Protein Alignment enc and Arpp21

DIOPT Version :10

• Sequence 1: NP_001261376.1
• Gene: enc / 44543
• FlyBaseID: FBgn0004875
• Length: 1942
• Species: Drosophila melanogaster
• Sequence 2: NP_001348949.1
• Gene: Arpp21 / 74100
• MGIID: 107562
• Length: 843
• Species: Mus musculus
• Alignment Length: 1098
• Identity: 262/1098 - (23%)
• Similarity: 400/1098 - (36%)
• Gaps: 361/1098 - (32%)

  Fly   209 TPAVIVTSQQPQQQQQQQQQQQQSVPPKPQQNVPLSNEA--EFPKLSPPKK--SGGQHNRTNSNG 269
            ||.::          ::.|.:.:|.|    :|..|.:|:  |..||...::  :..|..|.:.:|
Mouse     8 TPTIL----------EEGQTEPESAP----ENGILKSESLDEEEKLELQRRLAAQNQERRKSKSG 58

  Fly   270 SGMEFNNNNNSSNKKFVVDMKANGLDNKPHNNSSTGVIFNSGMNYKAAERHDRHERH-EMSS--- 330
            :|                         |.....|..|...|..........|:...| ::||
Mouse    59 AG-------------------------KGKLTRSLAVCEESSARSGGESHQDQESIHLQLSSFPS 98

  Fly   331 -QNSNLSNNHDEEPYHYEPRGGGGGKKHRANTNAKGNKPRLKNLGGSSSGSIDLGGGGGNGNCNN 394
             |..:.|...|.|          ..|:...|......:|:::.|
Mouse    99 LQEEDKSRKDDSE----------REKEKDKNREKLSERPKIRML--------------------- 132

  Fly   395 MSNNGQSNNSSNNTSGFISRVFHQSENSSEQYTDYGGTDLLVFFRDTLNKNPKDRNILLKIEKDL 459
                                    |::.|::|||..|.||..|..:||..|.:||.||||:|:::
Mouse   133 ------------------------SKDCSQEYTDSTGIDLHGFLINTLKNNSRDRMILLKMEQEM 173

  Fly   460 IDFVQENSRGCEYRFPPASSYNRMLIHRTAAFFGMEHNVDTETQQCVIVAVAKNTRIPEIRFQSL 524
            |||:.:::...: :||..|||.|||:||.||:||::|||| :|.:.||:....:|||||.||...
Mouse   174 IDFIADSNNHYK-KFPQMSSYQRMLVHRVAAYFGLDHNVD-QTGKSVIINKTSSTRIPEQRFCEH 236

  Fly   525 VRDD-----ARKSILKRDTHSFD-EVRQSPYLCPLSLDRKAKSFEEREEDYDRARSRIFSRTGGN 583
            ::|:     .::.|||||..|.| |..|...:.|...||::||.|||||:|.|.|.|||:
Mouse   237 LKDEKSEESQKRFILKRDNSSIDKEDNQQNRMHPFRDDRRSKSIEEREEEYQRVRERIFA----- 296

  Fly   584 HDGYSGGGGDEECYGGWEQQQQQQ-------KQSQPPRPKRPNGKML----QMQNSTESR--DGM 635
            ||...   ..|..:....:.|:..       |:.|..|..|.:....    |..:.||.|  |..
Mouse   297 HDSVC---SQESLFLDNSRLQEDMHICNETYKKRQLFRAHRDSSGRTSGSRQSSSETELRWPDHQ 358

  Fly   636 RSGGA-------------VPKSHNFGNYGGPPSSGGPGNNSLPRGDSTNSIKSGRGGFVKQDSTG 687
            |:..:             :.|:.:||           |...|.|||||:|.:|. |...|..|..
Mouse   359 RAWSSTDSDSSNRNLKPTMTKTASFG-----------GITVLTRGDSTSSTRSA-GKLSKTGSES 411

  Fly   688 STPWRLSPSSSGYKTRTQSVRSDSVTPSPTGYGSDRQTPELNHPSMMSHSRVAPPMSSGGGGVVG 752
            |:    |..|||..:||.                                    |.|:.....|.
Mouse   412 SS----SAGSSGSLSRTH------------------------------------PQSTALTSSVA 436

  Fly   753 GGGSGAVTVSSVEMGTEATGADPSSTSNCSSGTSGIVWAVTDISNVPIGSLLIDPQTLQPIVNAD 817
            .|..|.:..|...||.:   ..|||||.       |:..:...:.:|.||:|::|.|.||.||.|
Mouse   437 AGSPGCMAYSENGMGGQ---VPPSSTSY-------ILLPLESATGIPPGSILLNPHTGQPFVNPD 491

  Fly   818 GSIYHYDPSNLPPNQALQHSGNQYQSQNQGNSSSGGYNNYRKSSPHQQQQSQQQQQSQQHHQQ-Q 881
            |:...|:|..               ||.....:.||          |.||..|||.|.|..|| |
Mouse   492 GTPAIYNPPG---------------SQQTLRGTVGG----------QPQQPPQQQPSPQPQQQVQ 531

  Fly   882 LQQPQQLHQQSSQQYATTELSCSSTE----SYAEEE--AQSPGMECSEGYESYEQQSLPVQQQLS 940
            ..|||......:|...:.:.|..|.:    |:..:.  ..||            .|..|::::|:
Mouse   532 ASQPQMAGPLVTQSVQSLQPSSQSVQYPAVSFPPQHLLPMSP------------TQHFPLREELA 584

  Fly   941 GN----GDSASTKGDDCDSLASATACLSITTSTSTKNYDRIEVQKYKNQATSPNIPACCAVGEKL 1001
            ..    ..|..:.||..:..:......|:...|:       :.|.|          ...:.|::|
Mouse   585 AQFSQLSMSRQSSGDTPEPPSGTVYPASLLPQTA-------QPQSY----------VITSAGQQL 632

  Fly  1002 EL----EAGLPQEQEQEPMAGPSSSG----SATSSVGITELPSSQTPLPMVNQVNCDLQSVSPST 1058
            ..    ::|.|..| |...|.||..|    ...:.:.:...||.|.|
Mouse   633 STGGFSDSGPPISQ-QVLQAPPSPQGFVQQPPPAQMSVYYYPSGQYP------------------ 678

  Fly  1059 TPYSQCEVKTPSQNHAPSAAVEEPKTTTWTYTQSYQAPDGSTVFHTTTTPNGAAPYCATTYQQGP 1123
                    .:.||.:.|.|:|:      ::..:|.|.|.       ||...|..|  ..:.|||.
Mouse   679 --------TSTSQQYRPLASVQ------YSAQRSQQIPQ-------TTQQAGYQP--VLSGQQGF 720

  Fly  1124 DGSIYAVPQGMVYAAYPQPGVGTAGGA-------SQPLFQLTTSSHPPAQTIFASPEAGAEIPGG 1181
            .|.:     |:..:|:.|..:.:..||       |.|    |.||:....|     :....:|..
Mouse   721 QGMM-----GVQQSAHSQGVMSSQQGAPVHGVMVSYP----TMSSYQVPMT-----QGSQAVPQQ 771

  Fly  1182 TYMIPVFDPAQQPREGLIPA--QAIY-------------QTGPGGPGATTVMPMATAA 1224
            ||..|:..|: |..:|.:||  ..:|             ..||..|.:|  :|:.:|:
Mouse   772 TYQPPIMLPS-QAGQGSLPATGMPVYCNVTPPNPQNNLRLMGPHCPSST--VPVMSAS 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enc	NP_001261376.1	R3H_encore_like	448..508	CDD:100071	30/59 (51%)
		SUZ	530..578	CDD:463689	24/48 (50%)
		PRK10263	<1103..>1304	CDD:236669	35/144 (24%)
Arpp21	NP_001348949.1	R3H_encore_like	162..223	CDD:100071	31/62 (50%)
		SUZ	244..299	CDD:463689	26/59 (44%)
		PAT1	589..>818	CDD:401645	61/302 (20%)