Protein Alignment enc and arpp21

DIOPT Version :10

• Sequence 1: NP_001261376.1
• Gene: enc / 44543
• FlyBaseID: FBgn0004875
• Length: 1942
• Species: Drosophila melanogaster
• Sequence 2: XP_692585.5
• Gene: arpp21 / 564134
• ZFINID: ZDB-GENE-081104-296
• Length: 688
• Species: Danio rerio
• Alignment Length: 836
• Identity: 199/836 - (23%)
• Similarity: 301/836 - (36%)
• Gaps: 242/836 - (28%)

  Fly   357 HRANTNAKGNKPRLKNLGG--SSSGSIDLGGGGGNGNCNNMSNNGQSN--NSSNNTSGFISRVFH 417
            |...|..:.||.:|.....  ..|.|.|......:...:..||:|.|.  :.........|:...
Zfish    42 HEQLTKKQKNKGKLIRSVAVCDESVSTDENSKEKDSKTSISSNHGDSPVCDEVEEEKSITSKKTS 106

  Fly   418 QSENSSEQYTDYGGTDLLVFFRDTLNKNPKDRNILLKIEKDLIDFVQENSRGCEY-RFPPASSYN 481
            .|:..|.:|||..|.||..|...||..:|:||.:|||:|:|:.||:.:||   .| :||..|||:
Zfish   107 LSKEPSLEYTDSTGIDLEEFLITTLRSSPRDRLMLLKLEQDMTDFMTDNS---SYKKFPQMSSYH 168

  Fly   482 RMLIHRTAAFFGMEHNVDTETQQCVIVAVAKNTRIPEIRFQSLVRD---DARKSILKRDTHSFDE 543
            |||:||.||:||:||||| .:.:.||:....::||||.||...|::   :.|:.||:||  :..|
Zfish   169 RMLVHRVAAYFGLEHNVD-HSGKAVIINKTCSSRIPEHRFAEHVQEEKMEERRLILRRD--ASQE 230

  Fly   544 VRQSPYLCP-LSLDRKAKSFEEREEDYDRARSRIFSRTGGNHDGYSGGGGDEECYGGWEQQQQQQ 607
            ........| |....:::|.|||||:|.|.|.||||:             |..|.     .|...
Zfish   231 KEDGQLRVPSLKEQMRSRSIEEREEEYQRVRERIFSQ-------------DATCL-----SQSVY 277

  Fly   608 KQSQPPRPKRPNGKML-QMQNSTESRDGMRSGGAVPKSHNFGNYGGPPSSGGPGN---NSLPRGD 668
            .:::.|    .:|.:| :.|...:...|.|.|.        |...|...|....:   |:.||
Zfish   278 IETRGP----DDGSVLTETQRRRQLFRGERDGS--------GRLSGSRQSSFELDCHWNNDPR-- 328

  Fly   669 STNSIKSGRGGFVKQDSTGSTPWRLSPSSS-GYKTRTQSVRSDSVTPSPTGYGSDRQTPELNHPS 732
                                 ||..:.|.| .:.:::...|||
Zfish   329 ---------------------PWSSTDSDSPTWSSKSAHTRSD---------------------- 350

  Fly   733 MMSHSRVAPPMSSGGGGVVGGGGSGAVTVSSVEMGTEATGADPSSTSNCSSGTSGIVWAVTDISN 797
              |.|::..|               ||:.|::...       ||:.:| ::.|..||.|.   |:
Zfish   351 --SSSKLCKP---------------AVSDSALSYA-------PSNNNN-NNPTYIIVPAE---SS 387

  Fly   798 VPIGSLLIDPQTLQPIVNADGSIYHYDPSNLPPNQALQHSGNQYQSQNQGNSSSGGYNNYRKSSP 862
            :|.||:|::|.|.||.:|.||:...|:|   |.:|......|..|                   |
Zfish   388 IPPGSILLNPHTGQPFLNPDGTPAVYNP---PVSQKSSIQLNPVQ-------------------P 430

  Fly   863 HQQQQSQQQQQSQQHHQQQLQ-------QPQQLHQQSSQQYATTELSCSSTESYA------EEEA 914
            .......|||....|...|:|       .|||::..:|||....:.|...:..:|      :..|
Zfish   431 QAPPPPPQQQPIVSHGVPQVQYSSVSYLPPQQMNASTSQQLPVEQTSEDISAKFAHMTLSHQSSA 495

  Fly   915 QSPGMECSEGYESYEQQSLPVQQQLSGNGDSASTKGDDCDSLASATACLSITTSTSTKNYDRIEV 979
            ..|.|      .|:..|..|.....:.:..|.: .....:|..|....|:..|:...:|....:|
Zfish   496 DPPEM------SSFYMQGAPPTNTYAPHLHSYA-PSHQSESYMSPGMTLAPPTAPPPQNQQSSQV 553

  Fly   980 QKYKNQATSPNIPACCAVGEKLELEAGLPQEQEQEPMAGPSSSGSATSSVGITELPSSQTPLPMV 1044
            ..|       :.|..||...:....|....:...:|:.  |:.......:|...||.:|
Zfish   554 SVY-------SYPVQCASASQQYTAAAYGTQTGYQPVV--SNQQGCLGMMGSQVLPQTQ------ 603

  Fly  1045 NQVNCDLQSVSPSTTPYSQCEVKTPSQNHAPSAAVEEPKTTTWTYTQSYQAPDGSTVFHTTTTPN 1109
                   |.:..:   ||.                          ..|||.|     .|
Zfish   604 -------QGIMGA---YSS--------------------------VTSYQVP-----HH------ 621

  Fly  1110 GAAPYCATTYQQGPDGSIYAVPQGMVYAAYPQPGVGTAGGASQPLFQLTTSSHPPA 1165
                :.....||.|...:.:...|......|..||           ||..:|.||:
Zfish   622 ----HQQQQQQQHPSAMLVSGQGGQTQCMVPPAGV-----------QLYCNSPPPS 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enc	NP_001261376.1	R3H_encore_like	448..508	CDD:100071	32/60 (53%)
		SUZ	530..578	CDD:463689	19/48 (40%)
		PRK10263	<1103..>1304	CDD:236669	13/63 (21%)
arpp21	XP_692585.5	R3H_encore_like	137..197	CDD:100071	33/63 (52%)