Protein Alignment enc and r3hdm1

DIOPT Version :10

• Sequence 1: NP_001261376.1
• Gene: enc / 44543
• FlyBaseID: FBgn0004875
• Length: 1942
• Species: Drosophila melanogaster
• Sequence 2: XP_073793464.1
• Gene: r3hdm1 / 560062
• ZFINID: ZDB-GENE-030131-7119
• Length: 1142
• Species: Danio rerio
• Alignment Length: 1447
• Identity: 337/1447 - (23%)
• Similarity: 471/1447 - (32%)
• Gaps: 556/1447 - (38%)

  Fly   246 EAEFPKLSPPKKSGGQHNRTNSNGSGMEFNNNNNSSNKKFVVDMKANGLDNKPHNNSSTGVIFNS 310
            |::.|.::.|.        ...:.|....:.||.:..::.|.| :::....:|....||..|..|
Zfish    18 ESDGPHMAEPP--------ATLSDSQQHASQNNGTHTQECVTD-QSSSHQTQPQLGQSTQSIKRS 73

  Fly   311 GMNYK--------AAERHDRHERHEMSSQNSNLSNNHDEEPYHYEPRGGGGGKKHRANTNAKGNK 367
            ..|.|        ..|........|::         |::|..|.|.    ....|:..|:.| |:
Zfish    74 KSNGKLKLVRSLAVCEEPSPPTLRELT---------HEQEKLHIEL----SQAFHKEETSIK-NE 124

  Fly   368 PRLKNLGGSSSGSIDLGGGGGNGNCNNMSNNGQSNNSSNNTSGFISRVFHQSENSSEQYTDYGGT 432
            ...|                   :|:...   ::...|..|         .|.:.|::|||..|.
Zfish   125 DSQK-------------------SCDKPE---KTERLSKKT---------LSRDPSQEYTDSTGI 158

  Fly   433 DLLVFFRDTLNKNPKDRNILLKIEKDLIDFVQENSRGCEYRFPPASSYNRMLIHRTAAFFGMEHN 497
            ||..|..:||..||:||.:|||:|:|::||: .|....:.:|||.:||:|||:||.||:||::||
Zfish   159 DLHEFLVNTLKNNPRDRMMLLKLEQDILDFI-SNIESQKRKFPPMTSYHRMLLHRVAAYFGLDHN 222

  Fly   498 VDTETQQCVIVAVAKNTRIPEIRFQSLVRDD-----ARKSILKRDTHSFDE----VRQSPYLCPL 553
            || :|.:.||:....|||||:.:|...::||     .::.|||||..|.|:    :|..     |
Zfish   223 VD-QTGKSVIINKTSNTRIPDQKFSEHIKDDKTDDFQKRYILKRDNSSLDQDDGRLRMR-----L 281

  Fly   554 SLDRKAKSFEEREEDYDRARSRIFSRTGGNH--------------------------DGYSGGGG 592
            ..||::||.|||||:|.|||.|||::...:|                          ||.||...
Zfish   282 KDDRRSKSIEEREEEYQRARDRIFAQDVQDHFSFDKRIQEDMTFINTQQRRQIFRLRDGRSGNSR 346

  Fly   593 DEECYGGWEQQQQQQKQSQPPRPKRPNGKMLQMQNSTESRDGMRS-GGAVPKSHNFGNYGGPPSS 656
            .       ...:.:||.|.|    ||       .:||:|....|: ..|:.|:::|.
Zfish   347 Q-------SSSENEQKYSDP----RP-------WSSTDSDSSHRNLKPAMTKANSFS-------- 385

  Fly   657 GGPGNNSLPRGDSTNSIKS-GRGGFVKQDSTGSTPWRLSPSSSGYKTRTQSVRSDSVTPSPTGYG 720
               |.:.|.|||||.|.|| |:......||:.|.     .||||..:|...:.    .|.|.  .
Zfish   386 ---GISLLIRGDSTASSKSTGKLSKTSSDSSSSV-----GSSSGSLSRPAQLS----LPGPV--R 436

  Fly   721 SDRQTPELNHPSMMSHSRVAPPMSSGGGGVVGGGGSGAVTVSSVEMGTEATGADPSSTSNCSSGT 785
            .....|...|||       ||         :||                 :.|..|||:|.:...
Zfish   437 PFTMAPVAPHPS-------AP---------IGG-----------------SAASQSSTTNANINA 468

  Fly   786 SGIVWAV-TDISNVPIGSLLIDPQT-----LQPIVNADGSIYHYDPSNLPPNQALQHSGNQYQSQ 844
            :...:.| .|.|.:|.||:|::|||     .||.||.|||...|:|:
Zfish   469 NASFYIVPLDASAIPPGSVLLNPQTGLCYAGQPFVNPDGSPVVYNPA------------------ 515

  Fly   845 NQGNSSSGGYNNYRKSSPHQQQQSQQQQQSQQH---H-------QQQLQQPQQ----LHQQSS-- 893
                                  .:.||.:.|||   |       ...|..|.|    |..|||
Zfish   516 ----------------------MTSQQGRGQQHMTLHPAPPPPPPPPLPPPPQPANHLLAQSSAP 558

  Fly   894 --QQYATTELSC-----------SSTESYAEEEAQSPGMECSEGYESYEQQSLPVQQQLSGNGDS 945
              |..|...:||           :.|:.|.   .|..|:       |.:...:.:.:|.||....
Zfish   559 SVQFAAAAAVSCPPLLPPPAPPAAFTQQYT---VQQDGL-------SAQFSHMNLVRQASGEAPD 613

  Fly   946 ASTKGDDCDSLASATACLSITTSTSTKNYDRIEVQKYKNQATSPNIPACCAVGEKLELEAGLPQE 1010
            ..|      .|...:..|.                  .|||..|
Zfish   614 PHT------GLYPQSLLLQ------------------NNQAPPP--------------------- 633

  Fly  1011 QEQEPMAGPSSSGSATSSVGITELPS-----------------SQTPLPMVNQVNCDLQSVSPST 1058
              ..|...|..:|...||.|.|..|:                 .||||..|:...|.....|.||
Zfish   634 --APPPPPPPPTGYMISSAGQTISPAYQHHTAVNQTVLQPHAYMQTPLQQVSACYCAPGQFSHST 696

  Fly  1059 TPYSQCEVKTPSQNHAPSAAVEEPKTTTWTYTQSYQAPDGSTVFHTTTTPNGAAPYCATTYQQGP 1123
            ..|     :|....|             ::.|||.......|.|.|...|...:.......||..
Zfish   697 QHY-----RTGPPVH-------------YSATQSQTLAPQQTGFQTVMPPQAPSYQSMMGVQQNQ 743

  Fly  1124 DGSIYAVPQGM------VYAAYP---------QPG---VGTAGGASQPLFQLTTSSHPPAQTIFA 1170
            :.|:.:...|:      |...||         |.|   |..|....|.:.|..|:..|
Zfish   744 NQSLVSSQGGLTNQIQSVMVQYPTMHPYQVSVQQGSQSVPQAAYQQQIMLQGQTNQTP------- 801

  Fly  1171 SPEAGAEIPGGTY--MIPVFDPAQQPR----EGLIPAQAIYQTG-PGGPGATTVMPMATAAAYPT 1228
            :|.|..::    |  |:|   |.|...    .|.:|.....|.. |..|......|:       |
Zfish   802 APSASMQV----YYSMMP---PTQHSNISSAVGFLPHPGSEQMSFPRAPSPCGSQPI-------T 852

  Fly  1229 AQFATAAPNGAPIYQAPLIYSSEPGGGAQLQQL-------PMAPYPIQYSYPYYHPISYYV---- 1282
            ||..||.|            ...|.||..:.||       |.||.|     |::.|..||.
Zfish   853 AQQCTAVP------------PPPPAGGVVMMQLSVPPSQQPRAPTP-----PHWKPTRYYKPSDI 900

  Fly  1283 ---------PQQAVAAAPMVASQ-----------PQVGQAPM-------QQQAPHTGAGTTTGPP 1320
                     |||.::.:|..|..           |:.|.||.       :..||..|.|....||
Zfish   901 PPQDATQNNPQQLLSPSPSPAQSPAPAHLANLKGPRPGHAPFSIMPQFSRPYAPAPGQGDGRYPP 965

  Fly  1321 TVVSVSGQ-------------------QHHQPHQQHHQQQQHSSNGSVVTSSAYGTRVKRTPGGG 1366
            .:    ||                   .||..|..||.|
Zfish   966 LI----GQPLQYNPPIRPPLMHGSHVVNHHHHHHLHHHQ-------------------------- 1000

  Fly  1367 SIHYNPSYTPSSVAHAGGAHHPSAGSAQIIAAPAASTTTYHALPTLTLAHGGPATG-----TDLS 1426
                    .|..|.|.|....|        |....||         .::.|...||     |||.
Zfish  1001 --------GPVGVRHGGRPRRP--------AKKTLST---------DMSQGEMDTGRVLEVTDLP 1040

  Fly  1427 GAGGAHVYA---------LPAQHALIPTNIFPYAAAAAAAAGGPGGPPTTPQVVQQAPPPPPQSA 1482
             ||.:.|.|         :.|....:|..:.|             ..|...:|....|..|
Zfish  1041 -AGISRVEAETLLAELSKVGAVITWLPEPLSP-------------NQPEGAEVTNTEPTKP---- 1087

  Fly  1483 PHHAL---ITAAPFYPA 1496
            |||.|   .|....:|:
Zfish  1088 PHHDLASKYTILALFPS 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enc	NP_001261376.1	R3H_encore_like	448..508	CDD:100071	30/59 (51%)
		SUZ	530..578	CDD:463689	24/51 (47%)
		PRK10263	<1103..>1304	CDD:236669	57/256 (22%)
r3hdm1	XP_073793464.1	None