Protein Alignment enc and ZK121.2

DIOPT Version :9

• Sequence 1: NP_001261376.1
• Gene: enc / 44543
• FlyBaseID: FBgn0004875
• Length: 1942
• Species: Drosophila melanogaster
• Sequence 2: NP_498142.1
• Gene: ZK121.2 / 175734
• WormBaseID: WBGene00022664
• Length: 558
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 154/697 - (22%)
• Similarity: 226/697 - (32%)
• Gaps: 265/697 - (38%)

  Fly   272 MEFNNNNNSSNKKFVVDMKANGLDNKPHNNSSTGVIFNSGMNYKAAE----RHDRHERHEMSSQN 332
            |...|:.:..|...:.|::....|::  ..|:|.::..:.....|.|    |.:...|..:|.||
 Worm     1 MSTENDVSEENNSELDDVEDAKQDDR--RRSTTVIMTMNVTTVPATESEGVRRNGSVRRRLSKQN 63

  Fly   333 SNL-------------SNNHD------EEPYHYEPRGGGGGKKHRANTNAKGNKPRLKNLGGSSS 378
            :.:             |.|.|      ||    .|..|...:|...:::....:|
 Worm    64 ATIEEPISLLSISDSPSENSDTTVPCIEE----HPEEGKEEEKPAESSDVSKLRP---------- 114

  Fly   379 GSIDLGGGGGNGNCNNMSNNGQSNNSSNNTSGFISRVFHQSENSSEQYTDYGGTDLLVFFRDTLN 443
                               .|.:.|...:||..:||     |::..:|:|..|.||..|...||:
 Worm   115 -------------------PGLAQNKLWSTSKSLSR-----ESTGTEYSDRSGIDLRNFVDRTLH 155

  Fly   444 KNPKDRNILLKIEKDLIDFVQENSRGCEYRFPPASSYNRMLIHRTAAFFGMEHNVDTETQQCVIV 508
            |:.:||..||:.||.|.:.:.::|...: ||...|||:|||:||.||:||::||| |..|..::|
 Worm   156 KSEEDRKQLLEFEKQLKELILDDSTQSK-RFELPSSYHRMLLHRCAAWFGLDHNV-TNKQTDIVV 218

  Fly   509 AVAKNTRIPEIRFQSLVRDD--------------ARKSILKRDTHSFDEVRQSPYLCPLSLD--- 556
            ..::.|:||:..|...:|.|              :||.:  ....||.:...|.|....||:
 Worm   219 NKSEKTKIPDDNFTDYIRHDNYVEDRLKRQNTCGSRKEL--HHMESFGDHSTSQYGSQASLNHDL 281

  Fly   557 ---RKAKSFEEREEDYDRARSRIFSRTGGNHDGYSGGGGDEECYGGWEQQQQQQKQSQPPRPKRP 618
               |:|:||:            :.:.||                         ....||..|...
 Worm   282 LMMRRAQSFD------------VAAVTG-------------------------PSVIQPQSPHHV 309

  Fly   619 NG-KMLQMQNSTESRDGMRSGGAVPKSHNFGNYGGPPSSGGPGNNSLPRGDSTNSIKSGRGGFVK 682
            .| .|.|:..:...:..:.:..:.|:.|.:    .|..|....|||..
 Worm   310 RGLPMRQLSLNCPQQSMVTAPMSGPQGHQW----APQRSFDCSNNSYL----------------- 353

  Fly   683 QDSTGSTPWRLSPSSSG-------YKTRTQSVRSDSVTPSPTGYGSDRQTPELNHPSMMSHSR-- 738
              .||..|......|.|       :....|||        |...|    ||    ||:|.|..
 Worm   354 --CTGKHPMMRKAESFGGMANGISHGCYEQSV--------PVVCG----TP----PSVMVHHHHH 400

  Fly   739 ----VAPPMSSGGGGVVGGGGSGAVTVSSVEMGTEATGADPSST----SNCSSGTSGIVWAVTDI 795
                ..||.|:..|..|           ..||..      |||.    ..||.|.       |..
 Worm   401 HAHIQQPPTSNYTGYQV-----------FEEMSM------PSSNYQEPGMCSPGG-------TYY 441

  Fly   796 SNVPIGSLLIDPQTL--------QPIVNADGSIYHYDPSNLPPNQALQHSGNQYQ---------- 842
            ..||  ..::.||..        |......|..|.|.|.  ||.|.:     |||
 Worm   442 EYVP--QPVVQPQQYARPIRYMPQDYRRPQGVQYMYGPP--PPQQYM-----QYQPMVHPEVEVI 497

  Fly   843 ------------------SQNQGNSSS---------------GGYNN 856
                              .|.||.|||               |||.:
 Worm   498 VDPVQTQPFPQVSHFVLPDQQQGYSSSHQAETANSFIKASIDGGYGS 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
enc	NP_001261376.1	R3H_encore_like	448..508	CDD:100071	27/59 (46%)
		SUZ	527..578	CDD:289518	13/70 (19%)
ZK121.2	NP_498142.1	R3H_encore_like	160..221	CDD:100071	28/62 (45%)
		PRK10263	<391..>493	CDD:236669	33/134 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167320
Domainoid	1	1.000	46	1.000	Domainoid score	I8240
eggNOG	1	0.900	-	-		E1_KOG2953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001600
OrthoInspector	1	1.000	-	-		oto20568
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15672
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8676
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.920