Protein Alignment ct and NKX6-2

DIOPT Version :9

• Sequence 1: NP_524764.1
• Gene: ct / 44540
• FlyBaseID: FBgn0004198
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: NP_796374.2
• Gene: NKX6-2 / 84504
• HGNCID: 19321
• Length: 277
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 70/344 - (20%)
• Similarity: 105/344 - (30%)
• Gaps: 126/344 - (36%)

  Fly   744 SSTPTAAGNNNGSNNSS---------SNTNANSTAQLAASL-ASTLNGTKSLMQEDSNGLAAVAM 798
            ||.|.||.:|.....:|         :...|.:...|.|.| ..|.:|...::
Human    12 SSAPLAALHNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGISDIL------------ 64

  Fly   799 AAHAQHAAALGPGFLPGLPAFQFAAAQVA-----AGGDGRGHYRFADSELQLPPGASMAGR---L 855
               .:...|.|.|.|.|||.....|:...     |....||:.:         |.|.:.||   .
Human    65 ---GRPVGAAGGGLLGGLPRLNGLASSAGVYFGPAAAVARGYPK---------PLAELPGRPPIF 117

  Fly   856 GESLI---PKGDPMEAKLQEMLRYNMDKYANQALDTLHISRRVRELLSVHNIGQRLFA------- 910
            ...::   |..||         |......|...||.....:..|...|    ||::||
Human   118 WPGVVQGAPWRDP---------RLAGPAPAGGVLDKDGKKKHSRPTFS----GQQIFALEKTFEQ 169

  Fly   911 -KYILGLSQGTVSELL----SKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKSLIPKKDSGLP 970
             ||:.|..:..::..|    |:.|.|   .:..|..:||.||
Human   170 TKYLAGPERARLAYSLGMTESQVKVW---FQNRRTKWRKRHA----------------------- 208

  Fly   971 QYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRSHGGEDSHSNEDSKSPPQS 1035
                                    :..||:..||.|     :.|:...||.|: .::|..:.|..
Human   209 ------------------------VEMASAKKKQDS-----DAEKLKVGGSDA-EDDDEYNRPLD 243

  Fly  1036 CTSPFFKVENQLKQHQHLN 1054
            ..|...|:...||:|:..|
Human   244 PNSDDEKITRLLKKHKPSN 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527	20/80 (25%)
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
NKX6-2	NP_796374.2	Repressor domain. /evidence=ECO:0000250|UniProtKB:D3Z4R4	89..142		12/70 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..155		4/22 (18%)
		Homeobox	151..204	CDD:306543	14/59 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		12/45 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910