DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and six2a

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_571858.1	Gene:	six2a / 83415	ZFINID:	ZDB-GENE-010412-1	Length:	288	Species:	Danio rerio

Alignment Length:	249	Identity:	59/249 - (23%)
Similarity:	88/249 - (35%)	Gaps:	76/249 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1642 EAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASK---RR 1703
            :||:...:|:..||. |....|..| ....|.:: ||||. |:.:|..:|.........|   ||
Zfish    53 KAVVAFHRGNFRELY-KILESHQFS-PHNHPKLQ-QLWLK-AHYIEAEKLRGRPLGAVGKYRVRR 113

  Fly  1704 RSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDP 1768
            :                        .|.|.|:..|       ::....|.|:.:..||..:..:|
Zfish   114 K------------------------FPLPRSIWDG-------EETSYCFKEKSRSVLREWYTHNP 147

  Fly  1769 YPNVGTIEFLANELGLATRTITNWFHNHRMR-----LKQQV--------PHGP------------ 1808
            ||:......||...||.|..::|||.|.|.|     .|::.        .|.|
Zfish   148 YPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNTNSHNPLTSSMNGNKTIL 212

  Fly  1809 -AGQDNPIPS--RESTSATPFDPVQFRILLQQR--LLELH--KERMGMSGAPIP 1855
             :..|:..||  .:.||::|      .:||...  |..||  ....|.|..|:|
Zfish   213 GSSDDDKTPSGTPDHTSSSP------ALLLTSNSGLQSLHGLAPPPGPSAIPVP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	15/47 (32%)
		Homeobox	1749..1801	CDD:278475	18/56 (32%)
six2a	NP_571858.1	SIX1_SD	9..118	CDD:293483	20/92 (22%)
six2a	NP_571858.1	homeodomain	129..180	CDD:238039	18/50 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910