DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and LHX3

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_055379.1	Gene:	LHX3 / 8022	HGNCID:	6595	Length:	402	Species:	Homo sapiens

Alignment Length:	221	Identity:	47/221 - (21%)
Similarity:	70/221 - (31%)	Gaps:	71/221 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1745 SKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHR---MRLKQQVPH 1806
            :|:.|...:.:|.|.|:.|:...|.|.....|.|::|.||..|.:..||.|.|   .|||:....
Human   162 AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGR 226

  Fly  1807 GPAGQ----------------DNPIPSRESTSATPF--------------------DPVQFRILL 1835
            ...||                |:....::|.:...|                    :|.|.....
Human   227 QRWGQYFRNMKRSRGGSKSDKDSVQEGQDSDAEVSFPDEPSLAEMGPANGLYGSLGEPTQALGRP 291

  Fly  1836 QQRLLELHKERMGMS----------GAPIPYPPYFAAA-----------------AILGRSLAGI 1873
            ...|.....|..|::          |:|...||..||.                 ..||...:|.
Human   292 SGALGNFSLEHGGLAGPEQYRELRPGSPYGVPPSPAAPQSLPGPQPLLSSLVYPDTSLGLVPSGA 356

  Fly  1874 PGA-----AAAAGAAAAAAAVGASGG 1894
            ||.     ..|....::..:.|:|||
Human   357 PGGPPPMRVLAGNGPSSDLSTGSSGG 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475	18/54 (33%)
LHX3	NP_055379.1	LIM1_Lhx3b	33..87	CDD:188851
		LIM2_Lhx3_Lhx4	95..150	CDD:188762
		Homeobox	165..218	CDD:278475	17/52 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910