DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and lmx1ba

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001349521.1	Gene:	lmx1ba / 554361	ZFINID:	ZDB-GENE-050114-3	Length:	375	Species:	Danio rerio

Alignment Length:	181	Identity:	45/181 - (24%)
Similarity:	69/181 - (38%)	Gaps:	28/181 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1690 QLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPS-----KKQR 1749
            |||.....|..|...|  |:..|  ||.|.::..|.   .|..|:.|.|.|.....     |:.|
Zfish   139 QLLCKTDYEREKDLAS--PDLSD--SDKSEDEDLDV---KPEKGAGGQGKGSDDSKDPRRPKRPR 196

  Fly  1750 VLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQDNP 1814
            .:.:.:|:.|.:.:|.:...|.....|.||.|.||:.|.:..||.|.|.::|:........|:..
Zfish   197 TILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQEQQ 261

  Fly  1815 IPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAI 1865
            ...|                |.|.::....|.:..|..|:..||..|..::
Zfish   262 NSQR----------------LGQDVMSSRMENLMSSYTPLAPPPPHALVSM 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	45/181 (25%)
		Homeobox	1749..1801	CDD:278475	16/51 (31%)
lmx1ba	NP_001349521.1	LIM1_Lmx1b	33..85	CDD:188757
		LIM	92..146	CDD:295319	3/6 (50%)
		Homeobox	195..248	CDD:306543	16/52 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910