DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and crx

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001016021.1	Gene:	crx / 548775	XenbaseID:	XB-GENE-478452	Length:	290	Species:	Xenopus tropicalis

Alignment Length:	269	Identity:	58/269 - (21%)
Similarity:	97/269 - (36%)	Gaps:	46/269 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1723 NDFYTSSPGPGSVGSGVGGAPPSKKQ---RVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGL 1784
            |....:..|...:.|.||.....:||   |..|:..|.:.|...||...||::...|.:|.::.|
Frog    13 NGLTLAGTGMDLLHSAVGYPTTPRKQRRERTTFTRAQLDILEALFAKTRYPDIFMREEVALKINL 77

  Fly  1785 ATRTITNWFHNHRMRLKQQVPHGPAGQDNPIPSRESTS-----------------------ATPF 1826
            ....:..||.|.|.:.:||.... .||..|.|:::.||                       .||.
Frog    78 PESRVQVWFKNRRAKCRQQQQQS-TGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPS 141

  Fly  1827 DPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAAAAGA------AAA 1885
            ......:.:..          ..|.:|||.|...|....:.|| ||.|...:.|.|      .::
Frog   142 STASATVSIWS----------PASISPIPDPLSAATTPCMQRS-AGYPMTYSQAPAYTQSYGGSS 195

  Fly  1886 AAAVGASGGDELQALNQAFKEQMSGLD-LSMPTLKRERSDDYQDDLELEGGGHNLSDNESLEGQE 1949
            :...|...|..|..::.......:.|. ::.||:....|.. ...|..:|.|.:.....|::..:
Frog   196 SYFTGLDCGSYLSPMHPQLSAPGATLSPIATPTMGSHLSQS-PASLSAQGYGASSLGFTSVDCLD 259

  Fly  1950 PEDKTTDYE 1958
            .:|:|..::
Frog   260 YKDQTASWK 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475	15/51 (29%)
crx	NP_001016021.1	Homeobox	42..94	CDD:395001	15/51 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..144		10/51 (20%)
		TF_Otx	154..236	CDD:397546	20/82 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910