Protein Alignment ct and PBX2

DIOPT Version :9

• Sequence 1: NP_524764.1
• Gene: ct / 44540
• FlyBaseID: FBgn0004198
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: NP_002577.2
• Gene: PBX2 / 5089
• HGNCID: 8633
• Length: 430
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 100/520 - (19%)
• Similarity: 171/520 - (32%)
• Gaps: 168/520 - (32%)

  Fly  1431 GSPQMPQGLASKMQAASLPMQKM-MSELKLQEPAQAQHLM--QQMQAAAMSAAMQ-QQQVAQAQQ 1491
            ||..:|.| ..|.....:..|.| :::..|.|....:|.:  .:|:.|..|...: :::...:.:
Human    40 GSGGVPGG-RGKQDIGDILQQIMTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIR 103

  Fly  1492 QAQQAQQAQQHLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAIS 1556
            .:|:.:.....|.:.....|.:     ....|.:....|||||||
Human   104 SSQEEEPVDPQLMRLDNMLLAE-----GVAGPEKGGGSAAAAAAA-------------------- 143

  Fly  1557 LPPSAGGAQPGGPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDTHD 1621
             ..|.||..|        .::..:|:.:..|..:      |.:: |.....||.|.       ::
Human   144 -AASGGGVSP--------DNSIEHSDYRSKLAQI------RHIY-HSELEKYEQAC-------NE 185

  Fly  1622 ITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPW-HMLSIKGRE-PFIRMQLWLSDAN 1684
            .||.:...|...:..:.:                  .||.. .|:||..|: ..|:|||   ..:
Human   186 FTTHVMNLLREQSRTRPV------------------APKEMERMVSIIHRKFSAIQMQL---KQS 229

  Fly  1685 NVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQR 1749
            ..|.:.:|::...:|.::||        |.|..::...|:::.|
Human   230 TCEAVMILRSRFLDARRKRR--------NFSKQATEVLNEYFYS--------------------- 265

  Fly  1750 VLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHGPAGQD-N 1813
                          ...:|||:....|.||.:.|:....::|||.|.|:|.|:.:  |...:: |
Human   266 --------------HLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNI--GKFQEEAN 314

  Fly  1814 PIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGIPGAAA 1878
            ....:.:.|.|                     :.|.|....|.||          |.||..|:..
Human   315 IYAVKTAVSVT---------------------QGGHSRTSSPTPP----------SSAGSGGSFN 348

  Fly  1879 AAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNE 1943
            .:|:......:....||...|      .|:..|..||      ....|.|:|   |||...|..|
Human   349 LSGSGDMFLGMPGLNGDSYSA------SQVESLRHSM------GPGGYGDNL---GGGQMYSPRE 398

  Fly  1944  1943
            Human   399  398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	14/75 (19%)
		Homeobox	1749..1801	CDD:278475	13/51 (25%)
PBX2	NP_002577.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52		5/12 (42%)
		PBC	50..243	CDD:397732	46/261 (18%)
		homeodomain	245..305	CDD:238039	20/102 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	326..347		9/30 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..430		10/30 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910