Protein Alignment ct and PBX1

DIOPT Version :9

• Sequence 1: NP_524764.1
• Gene: ct / 44540
• FlyBaseID: FBgn0004198
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: XP_005245285.1
• Gene: PBX1 / 5087
• HGNCID: 8632
• Length: 486
• Species: Homo sapiens
• Alignment Length: 623
• Identity: 107/623 - (17%)
• Similarity: 193/623 - (30%)
• Gaps: 228/623 - (36%)

  Fly  1462 PAQAQHLMQQMQAAAMSAAMQQ------QQVAQAQQQAQQAQQAQQH------------------ 1502
            |..:|||.............:|      ||:.....|:....||::|
Human    20 PGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEI 84

  Fly  1503 -----LQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAA--------LHH--------------- 1539
                 |::...::......|..:.....:|...::|:.:        .||
Human    85 KEKTELKEARSRNCPSLFFLVTRIQSSVRHRVLSSASTSGNPVTPQPTHHHPSFGWGEGKVLSIR 149

  Fly  1540 --QSMLLTSPGLPPQHAISLPPSAGGAQPGG----------PGGNQGSSNP-SNSEKKPMLMPVH 1591
              |....|.|.|.....:.|.....|.:.||          ..|..||.|. .:|:.:..|
Human   150 GAQEEEPTDPQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKL---- 210

  Fly  1592 GTNAMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELL 1656
              :.:|.:: |.....||.|.       ::.||.:...                 |.:.|.:..:
Human   211 --SQIRQIY-HTELEKYEQAC-------NEFTTHVMNL-----------------LREQSRTRPI 248

  Fly  1657 SKPKPWHMLSIKGRE-PFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSN 1720
            |..:...|:||..|: ..|:|||   ..:..|.:.:|::...:|.::||        |.:..::.
Human   249 SPKEIERMVSIIHRKFSSIQMQL---KQSTCEAVMILRSRFLDARRKRR--------NFNKQATE 302

  Fly  1721 DTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLA 1785
            ..|:::.|                                   ...:|||:....|.||.:.|:.
Human   303 ILNEYFYS-----------------------------------HLSNPYPSEEAKEELAKKCGIT 332

  Fly  1786 TRTITNWFHNHRMRLKQQVPHGPAGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMS 1850
            ...::|||.|.|:|.|:.:  |...::..|
Human   333 VSQVSNWFGNKRIRYKKNI--GKFQEEANI----------------------------------- 360

  Fly  1851 GAPIPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSM 1915
                    |.|..|:...::       :|.|:.|.:.:...|.|.     :.:|....|| ||.|
Human   361 --------YAAKTAVTATNV-------SAHGSQANSPSTPNSAGS-----SSSFNMSNSG-DLFM 404

  Fly  1916 PTLKRERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVRSS 1980
             :::....|.||.   .:.|.:..|..::|  :....:|..|     ...|||:..|
Human   405 -SVQSLNGDSYQG---AQVGANVQSQVDTL--RHVISQTGGY-----SDGLAASQMY-------- 450

  Fly  1981 RRKPAAPQWVNPAGA---VTNPSAVVAAVAAAAAAAAD 2015
                 :||.::..|.   .|.||:|.:......:..:|
Human   451 -----SPQGISANGGWQDATTPSSVTSPTEGPGSVHSD 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	14/74 (19%)
		Homeobox	1749..1801	CDD:278475	13/51 (25%)
PBX1	XP_005245285.1	PBC	40..288	CDD:281746	47/281 (17%)
		homeodomain	290..350	CDD:238039	19/102 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910