DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and PAX4

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001353039.1	Gene:	PAX4 / 5078	HGNCID:	8618	Length:	351	Species:	Homo sapiens

Alignment Length:	230	Identity:	54/230 - (23%)
Similarity:	79/230 - (34%)	Gaps:	59/230 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1644 VLGLSQGSVSELLSK--------PKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNE----- 1695
            :|.:|.|.||::|.:        ||     .|.|.:|      .|:....|.|:..||.|
Human    46 ILKVSNGCVSKILGRYYRTGVLEPK-----GIGGSKP------RLATPPVVARIAQLKGECPALF 99

  Fly  1696 RREASKRRRSTGPNQQDNSSDTSS---------NDTNDFYTSSPGPGSVGSGV-----GGAPP-- 1744
            ..|..::..:.|...||.:...||         .|.....|....|..:...|     |...|
Human   100 AWEIQRQLCAEGLCTQDKTPSVSSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRG 164

  Fly  1745 -----SKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHR------- 1797
                 ..:.|.:||..|.|||...|....||:......||....|...|:..||.|.|
Human   165 THPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQE 229

  Fly  1798 -MRLKQQVPHGPAGQDNP------IPSRESTSATP 1825
             ::.:.|:|....|...|      |.:::|..:.|
Human   230 KLKWEMQLPGASQGLTVPRVAPGIISAQQSPGSVP 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	14/53 (26%)
		Homeobox	1749..1801	CDD:278475	18/59 (31%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	23/93 (25%)
PAX4	NP_001353039.1	Homeobox	174..226	CDD:306543	18/51 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910