DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and DUXA

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001012747.1	Gene:	DUXA / 503835	HGNCID:	32179	Length:	204	Species:	Homo sapiens

Alignment Length:	191	Identity:	43/191 - (22%)
Similarity:	64/191 - (33%)	Gaps:	51/191 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1658 KPKPWH------MLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSD 1716
            ||.|.:      .|.|...|.  |:|:|..:.......|    :|.||.....|....|.....:
Human    37 KPYPGYATKQKLALEINTEES--RIQIWFQNRRARHGFQ----KRPEAETLESSQSQGQDQPGVE 95

  Fly  1717 TSSNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANE 1781
            ..|.:                       :::.|..:|..|...|..||..:|||.:.:.|.||.|
Human    96 FQSRE-----------------------ARRCRTTYSASQLHTLIKAFMKNPYPGIDSREELAKE 137

  Fly  1782 LGLATRTITNWFHNHRMRLKQQ----------------VPHGPAGQDNPIPSRESTSATPF 1826
            :|:....:..||.|.|.||..|                :|.|..|.::.......||.:.|
Human   138 IGVPESRVQIWFQNRRSRLLLQRKREPVASLEQEEQGKIPEGLQGAEDTQNGTNFTSDSHF 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	9/37 (24%)
		Homeobox	1749..1801	CDD:278475	19/51 (37%)
DUXA	NP_001012747.1	homeodomain	16..74	CDD:238039	10/42 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	73..101		7/54 (13%)
		Homeobox	105..155	CDD:278475	18/49 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	163..204		6/36 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910