DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and AgaP_AGAP000061

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_001237363.3	Gene:	AgaP_AGAP000061 / 4576053	VectorBaseID:	AGAP000061	Length:	673	Species:	Anopheles gambiae

Alignment Length:	583	Identity:	132/583 - (22%)
Similarity:	189/583 - (32%)	Gaps:	219/583 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   525 ERPMDASSNADLPESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDE---------- 579
            :||...||....|:::|:  .|:..::...||:.....:.:|....|.|..|:..
Mosquito     7 DRPCVISSGNFFPQNSKS--SAKQQQQQHTQAISKHLTQKDDPHLHSPHHQDQSSLGEIEVILVQ 69

  Fly   580 -------------DEDREAVN-------------ATTTDSNELKIKKEQHSPLDLNV-------- 610
                         .|..:.:|             ..::|...|....::.||:.||.
Mosquito    70 QHKQDALSVIIHPQESMQQINMCLGSQNPGSVDSMMSSDFQTLSPMHDRDSPVSLNTNTSYATLT 134

  Fly   611 -LSPNSAIAAAAAAAAAAACANDPNKFQAL-------LIERTKALAAEAL-------KNGASDAL 660
             |.|...|:..:...|.:...|....|..:       .||.......|.|       ...|...|
Mosquito   135 PLQPLPPISTMSDKFAYSIGGNICEAFPGINSGAVGVNIEINSCYNLEKLGVIHSPVHLSAVQEL 199

  Fly   661 SED------AHHQQQQHHQQQHQHQQQH--HQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHH-- 715
            |.|      :||.||||.|||.|.||||  ||||..|||||||                .|||
Mosquito   200 SPDGGDVVHSHHHQQQHQQQQQQQQQQHQQHQQQQQHQQHHHH----------------HHHHPD 248

  Fly   716 -----GHHLHGHGLLHPSSAHHLHHQTTESNSNSSTPT-----AAGNNNGSNNSSSNTN------ 764
                 ||.|..|||     ..||      :......||     ..|...|.....:.|.
Mosquito   249 VLQEKGHGLKEHGL-----KEHL------AGGPDKDPTLQDADIKGGGGGGGGGGAGTGDPCILV 302

  Fly   765 ----------ANSTAQLAA-----SLASTLNGTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLP 814
                      ..|..:|..     ......:||...: |..||...|.      |....|.|  |
Mosquito   303 RGSPGLDDRFLGSGKELVVRHHPKDDGEQFSGTVQYL-EHPNGSDVVL------HGTGNGTG--P 358

  Fly   815 GLPAFQFAAAQVAAGGDGRG------------HYR----------------------------FA 839
            |       ....:.||.|.|            |::                            :.
Mosquito   359 G-------GGDSSGGGGGGGGGSSGGILTGKEHHQSVFLNKSFSSKTNISDLNLCKEIVIDDVYE 416

  Fly   840 DSELQ-----------------LPPGASMAGRLGESLIPKGDP--MEAKLQEMLRYNMDKYANQA 885
            :|||.                 ...|.:.||:.| |.:..||.  :...|:|
Mosquito   417 ESELDHVKLEEKKLEESCNQPLTNGGGAAAGKSG-SCVSLGDVGCLNGDLEE------------- 467

  Fly   886 LDTLHISRRVRELLSVHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAW 948
            ::|..::.|:...|..::|.|.:||:.:|..||||:|:||..||||.|| :.||:::|:|:.|
Mosquito   468 INTKELAHRISSELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFRRMYKW 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527	26/63 (41%)
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
AgaP_AGAP000061	XP_001237363.3	CUT	464..538	CDD:280527	28/80 (35%)
AgaP_AGAP000061	XP_001237363.3	HOX	562..617	CDD:197696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910