DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and LMO1

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_006718291.1	Gene:	LMO1 / 4004	HGNCID:	6641	Length:	193	Species:	Homo sapiens

Alignment Length:	169	Identity:	39/169 - (23%)
Similarity:	61/169 - (36%)	Gaps:	53/169 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   810 PGFLPGLPAFQFAAAQVAAGGDGRGHYRFADSELQLPP----------GASMAGRLGESLIPKGD 864
            |.:||              .|:.||.   |.|:|:|..          |.:..|....|:.|||.
Human    10 PQWLP--------------AGEPRGR---AWSDLELGEVDVLGWKSGLGGAHWGVPMLSVQPKGK 57

  Fly   865 P-----MEAKLQEMLRY---NMDKYANQ-ALDTLHISRRVRELLSVHNIGQRLFAKYILGLSQ-- 918
            .     ...|:::  ||   .:|||.:: .|.......|:.|      :|..|:.|..|.|.:
Human    58 QKGCAGCNRKIKD--RYLLKALDKYWHEDCLKCACCDCRLGE------VGSTLYTKANLILCRRD 114

  Fly   919 -----GTVSE--LLSKPKPWDKLTEKGRDSYRKMHAWAC 950
                 ||...  ..||..|..::..:.||:...:..:||
Human   115 YLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFAC 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527	17/74 (23%)
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
LMO1	XP_006718291.1	LIM1_LMO1_LMO3	61..115	CDD:188774	14/61 (23%)
LMO1	XP_006718291.1	LIM2_LMO1_LMO3	125..179	CDD:188775	7/29 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910