DRSC/TRiP Functional Genomics Resources

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Protein Alignment ct and LHX1

DIOPT Version :9

Sequence 1:NP_524764.1 Gene:ct / 44540 FlyBaseID:FBgn0004198 Length:2175 Species:Drosophila melanogaster
Sequence 2:NP_005559.2 Gene:LHX1 / 3975 HGNCID:6593 Length:406 Species:Homo sapiens


Alignment Length:370 Identity:79/370 - (21%)
Similarity:125/370 - (33%) Gaps:127/370 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly  1638 KIFGEAVLGLSQG-SVSELL--SKPKPWHM----LSIKGREPFIRMQLWLSDANN-VERLQLLKN 1694
            :.||....|.:|| |.|:|:  ::.|.:|:    ..:..::.....:|::.|.|. |.:...|.|
Human    57 RCFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSN 121

  Fly  1695 E--RREASKRRRSTG--PNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVG-----GAPPSKKQRV 1750
            .  .:|.|....:||  |:...:|.|.|.:|..|..:::......||...     || ..:..|.
Human   122 SSVAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGA-KRRGPRT 185

  Fly  1751 LFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHR---MRLKQ---------- 1802
            ....:|.|.|:.|||..|.|.....|.||.|.||..|.|..||.|.|   .|:||          
Human   186 TIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHA 250

  Fly  1803 -------------------QVPHGP---------------------------------------- 1808
                               .:|:||                                        
Human   251 FFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGGNYDFFPQGPPSSQAQTPVDLPFVP 315

  Fly  1809 ---------AGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAP---IPYPPYFA 1861
                     .|.::|:|....:|..            ||..::.....|.|.:|   :|.|.:..
Human   316 SSGPSGTPLGGLEHPLPGHHPSSEA------------QRFTDILAHPPGDSPSPEPSLPGPLHSM 368

  Fly  1862 AAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQ---ALNQA 1903
            :|.:.|.|   .|.::.:...       |||.|:.|.   .:|:|
Human   369 SAEVFGPS---PPFSSLSVNG-------GASYGNHLSHPPEMNEA 403

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ctNP_524764.1 CUT 886..955 CDD:280527
CUT 1335..1411 CDD:280527
CUT 1616..1690 CDD:280527 14/59 (24%)
Homeobox 1749..1801 CDD:278475 22/54 (41%)
LHX1NP_005559.2 LIM1_Lhx1_Lhx5 4..55 CDD:188753
LIM2_Lhx1_Lhx5 63..118 CDD:188761 12/54 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 128..187 14/59 (24%)
Homeobox 183..236 CDD:278475 21/52 (40%)
An_peroxidase_like <291..>382 CDD:265428 15/105 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 293..374 12/92 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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