DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and so

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_476733.1	Gene:	so / 35662	FlyBaseID:	FBgn0003460	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	496	Identity:	101/496 - (20%)
Similarity:	165/496 - (33%)	Gaps:	149/496 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   323 QHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQHVASSAEDDDCANNNT 387
            ||...|..||.....|...:...:..::.|..:.|.:..|||                   |||:
  Fly     3 QHPATDFYDLAAANAAAVLTARHTPPYSPTGLSGSVALHNNN-------------------NNNS 48

  Fly   388 NTSNNNNTSNTATSNTNNN-----NNNNSSSGNSEKRKKKNNNNNNGQPAVLLAAKDKEIKALLD 447
            :||||||::....::....     :.|:||:|...........:...:.........:::..:.:
  Fly    49 STSNNNNSTLDIMAHNGGGAGGGLHLNSSSNGGGGGGVVSGGGSGGRENLPSFGFTQEQVACVCE 113

  Fly   448 ELQRLRAQEQTHLVQIQRLEEHLEVKRQHIIRLEARLDKQQINEALAEATALSAAASTNN----- 507
            .||:..        .|:||...|....|        .||.|:||::.:|.|:.|......
  Fly   114 VLQQAG--------NIERLGRFLWSLPQ--------CDKLQLNESVLKAKAVVAFHRGQYKELYR 162

  Fly   508 --NNNSQSSDNNKKLN--------TAAE----RPMDASSNADLPESTKAPVPAEDDEE------D 552
              .::..|:.|:.||.        ..||    ||:.|.....:......|....|.||      :
  Fly   163 LLEHHHFSAQNHAKLQALWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKE 227

  Fly   553 EDQAMLVD--SEEAEDKPEDSHHDDDEDEDEDREAVNATTTD-SNELKIKKEQHSPLDLNVLSPN 614
            :.:::|.|  |......|.:..        :..||...|||. ||..|.::::..
  Fly   228 KSRSVLRDWYSHNPYPSPREKR--------DLAEATGLTTTQVSNWFKNRRQRDR---------- 274

  Fly   615 SAIAAAAAAAAAAACANDPNKFQALLIERTKALAAEALKNGASDA----LSEDAHHQQQQHHQQQ 675
                                             |||. |:|::|.    .|.|:..:......|.
  Fly   275 ---------------------------------AAEH-KDGSTDKQHLDSSSDSEMEGSMLPSQS 305

  Fly   676 HQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSS----AHHLHHQ 736
            .|||||..||||           .|.:.|.:|         :.||...|.|.::    .||.|..
  Fly   306 AQHQQQQQQQQH-----------SPGNSSGNN---------NGLHQQQLQHVAAEQGLQHHPHQP 350

  Fly   737 TTESN-SNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLA 776
            ...|| :|.:...::|...|...|::.........|.|::|
  Fly   351 HPASNIANVAATKSSGGGGGGGVSAAAAAQMQMPPLTAAVA 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
so	NP_476733.1	SIX1_SD	103..212	CDD:293483	24/124 (19%)
so	NP_476733.1	homeodomain	223..274	CDD:238039	12/58 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910