DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and tup

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001286068.1	Gene:	tup / 35147	FlyBaseID:	FBgn0003896	Length:	534	Species:	Drosophila melanogaster

Alignment Length:	522	Identity:	104/522 - (19%)
Similarity:	159/522 - (30%)	Gaps:	202/522 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 QQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSRKNNNGGNESEQHVASSAEDDDCANNNTNTS 390
            ::|.:.||::..:...|.:|.:|:|.:.||                            |||||.|
  Fly   168 KEDHDVLEKSSQSSLTSSSVESNNNISSSN----------------------------NNNTNLS 204

  Fly   391 NNNNTSNTATSNTNNNNNNNSSSGNSEK-RKKKNNNNNNGQPAVLLAAKDKEIKALLDELQRLRA 454
            |||::|...:.     :::.|.||:.:. |.|:.:..::|:|.        .::.:|:|
  Fly   205 NNNHSSELGSM-----SDSGSESGSHKSIRDKRPSGPSDGKPT--------RVRTVLNE------ 250

  Fly   455 QEQTHLVQIQRLEEHLEVKRQHIIR----LEARLDKQQINEALAEATALSAAASTNNNNNSQSSD 515
                              |:.|.:|    ...|.| ..:.|.|.|.|:||.........|.:..|
  Fly   251 ------------------KQLHTLRTCYNANPRPD-ALMKEQLVEMTSLSPRVIRVWFQNKRCKD 296

  Fly   516 NNK----KLNTAAE---RPMDASSNADLPESTKAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHH 573
            ..|    ||....|   |.:...:...:|....:||                           .|
  Fly   297 KKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPV---------------------------RH 334

  Fly   574 DDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAAAAAAAAAAACANDPNKFQA 638
            |                             |||:|..|                    |...:|
  Fly   335 D-----------------------------SPLNLQGL--------------------DVQTYQ- 349

  Fly   639 LLIERTKALAAEAL-----KNGASDALSEDAHHQ--QQQH------------HQQQHQHQQQHHQ 684
               ...|||:..||     .|||.:. ...|..|  .|.|            |...|..|...||
  Fly   350 ---PPWKALSDFALHADLDSNGAINT-HTPAFQQLVNQMHGYDLNGMPILPPHPHSHPAQGPPHQ 410

  Fly   685 QQHLHQQHHHHLQQQPN---SGSNSNPASNDHHHGHHLHGHG-----------LLHPSSAHHLHH 735
            ........|:|..||||   .||:.:.....|||......:.           .|.|||:    .
  Fly   411 HPPPPGGPHNHQNQQPNQQPGGSSLDSGITSHHHPDSTDSYVTYLESDDKSKLALTPSSS----S 471

  Fly   736 QTTESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGLAAVAMAA 800
            ..:...|.||.|:..|...|      ......:..|...:.:..:.|:.|||.......:.:.|:
  Fly   472 SASAGTSISSPPSGVGAGGG------GAVGGGSGVLGLGVVANQSATEQLMQMLQKVTGSASPAS 530

  Fly   801 HA 802
            ||
  Fly   531 HA 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
tup	NP_001286068.1	LIM1_Isl	54..108	CDD:188752
		LIM2_Isl	116..171	CDD:188760	0/2 (0%)
		HOX	241..297	CDD:197696	15/88 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910