DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and AgaP_AGAP005346

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	XP_555988.2	Gene:	AgaP_AGAP005346 / 3289950	VectorBaseID:	AGAP005346	Length:	461	Species:	Anopheles gambiae

Alignment Length:	517	Identity:	115/517 - (22%)
Similarity:	157/517 - (30%)	Gaps:	159/517 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1631 LANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKG-----------------------REP 1672
            :|||..:..|          |:..||:||......|...                       ...
Mosquito    19 VANNRVKNSF----------SIEHLLAKPDRSGTASTSSAGCYRGMDDRLASSYPIAHPAQLHNS 73

  Fly  1673 FIRMQLWLSDANNVERLQLLKNER--------REASKRRRSTGPNQQDNSSDTSSNDTNDFYTSS 1729
            .:...|....|:.||.|.:.|||.        |..|:|..|:.|....|      .||.|..:..
Mosquito    74 MVYQTLMTRSASAVEFLDVNKNETSAVPFAADRPPSERAESSSPESSCN------EDTMDNCSEI 132

  Fly  1730 PGPGSVGSGVGGAPPSKKQ-RVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWF 1793
            ...||...|:......||: |..||..|.:||...|....|.:|.....||.:|.|....|..||
Mosquito   133 ASEGSASGGLAAHDDRKKRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLHLTETQIKIWF 197

  Fly  1794 HNHRMRLKQ---------------QVPHGPAGQDNPIPSR-ESTSATPFDPVQFRILLQQRLLEL 1842
            .|.|.:.|:               |:..|...:...:..| ...|.||..|...:.||      |
Mosquito   198 QNRRTKWKRKYTADVESLASHYYSQLGIGSFARPMVVGDRLWLFSQTPNGPTPVQSLL------L 256

  Fly  1843 HKERMGMSGA---------------------PIP------YPPYFAAAAILGRSLAGIPGAAAAA 1880
            :..:.|.:||                     |||      :||           ..|:|..|..:
Mosquito   257 NGPQPGAAGASHPALGMQHPAAIRPYPTLSGPIPMNAGPNFPP-----------RPGMPPGAYLS 310

  Fly  1881 GAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGHNLSDNESL 1945
            ...:||||  ..||                      .|.:..|...|..:....|...||..|.|
Mosquito   311 SIPSAAAA--GPGG----------------------FLHKIPSPSPQSRMAQPHGLRPLSSGELL 351

  Fly  1946 EGQ------EPEDKTTDYEKVLHKSALAAAAAYMSNAVRSSRRKPAAPQWVNPAGAVTNPSAVVA 2004
            ||.      .|..|....|  |....|.|.....|......|             |..|||.::.
Mosquito   352 EGAYYTAAGMPGPKFNPNE--LINGGLLATDGNSSGIADLER-------------AFGNPSNMIE 401

  Fly  2005 AVAAAAAAAADNERIINGVCVMQASEYGRDDTDSNK-PTDGGNDSDHEHAQLEIDQRFMEPE 2065
            ::|.:....|.   |..|  |....:.|.|..::|: ....|..|..:.:..|||...:|.|
Mosquito   402 SLATSNPTEAS---IAGG--VRTGGKKGADLMNNNECAIKDGLASSEQDSSSEIDCEEIEDE 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	14/81 (17%)
		Homeobox	1749..1801	CDD:278475	18/51 (35%)
AgaP_AGAP005346	XP_555988.2	Homeobox	152..205	CDD:278475	18/52 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910