DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ct and exd

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_001259592.1	Gene:	exd / 32567	FlyBaseID:	FBgn0000611	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	96/531 - (18%)
Similarity:	177/531 - (33%)	Gaps:	186/531 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly  1420 PEKLMRTGSYSGSPQMPQGLASKMQAASLPMQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQ 1484
            |.:::   :::|....|||.....|...   |...||.::::......::||:    ||.:.|..
  Fly     4 PNRML---AHTGGMMAPQGYGLSGQDDG---QNAGSENEVRKQKDIGEILQQI----MSISEQSL 58

  Fly  1485 QVAQAQQQAQQAQQAQQ-------HLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSM 1542
            ..|||::......:.:.       .::::....::..|   :::.|..|         .:...:|
  Fly    59 DEAQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQ---EEEPPDPQ---------LMRLDNM 111

  Fly  1543 LLTSPGLPPQH--AISLPPSAGGAQPGGPGGNQGSSNP-SNSEKKPMLMPVHGTNAMRSLHQHMS 1604
            |:......|:.  ..:...||..|..||.....|:.|. .:|:.:..|..:.     :..||.:.
  Fly   112 LIAEGVAGPEKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIR-----QIYHQELE 171

  Fly  1605 P--------TVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKP 1661
            .        |.:.|..|.:...|..||.|..|.::  .|..|.|..
  Fly   172 KYEQACNEFTTHVMNLLREQSRTRPITPKEIERMV--QIIHKKFSS------------------- 215

  Fly  1662 WHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFY 1726
                        |:|||   ..:..|.:.:|::...:|.::||        |.|..:|...|:::
  Fly   216 ------------IQMQL---KQSTCEAVMILRSRFLDARRKRR--------NFSKQASEILNEYF 257

  Fly  1727 TSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITN 1791
            .|                                   ...:|||:....|.||.:.|:....::|
  Fly   258 YS-----------------------------------HLSNPYPSEEAKEELARKCGITVSQVSN 287

  Fly  1792 WFHNHRMRLKQQVPHGPAGQD-NPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAP-- 1853
            ||.|.|:|.|:.:  |.|.:: |...::::..|:|:                     .|:|.|
  Fly   288 WFGNKRIRYKKNI--GKAQEEANLYAAKKAAGASPY---------------------SMAGPPSG 329

  Fly  1854 ------IPYPPYFAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLD 1912
                  .|.||         :...|.|              :|:.|.|:    .|.:...|.|.|
  Fly   330 TTTPMMSPAPP---------QDSMGYP--------------MGSGGYDQ----QQPYDNSMGGYD 367

  Fly  1913 LSMPTLKRERS 1923
               |.|.::.|
  Fly   368 ---PNLHQDLS 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	13/73 (18%)
		Homeobox	1749..1801	CDD:278475	13/51 (25%)
exd	NP_001259592.1	PBC	41..237	CDD:397732	42/252 (17%)
exd	NP_001259592.1	homeodomain	239..299	CDD:238039	21/102 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910