Protein Alignment ct and HOXD3

DIOPT Version :9

• Sequence 1: NP_524764.1
• Gene: ct / 44540
• FlyBaseID: FBgn0004198
• Length: 2175
• Species: Drosophila melanogaster
• Sequence 2: NP_008829.3
• Gene: HOXD3 / 3232
• HGNCID: 5137
• Length: 432
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 112/541 - (20%)
• Similarity: 163/541 - (30%)
• Gaps: 199/541 - (36%)

  Fly  1491 QQAQQAQQAQQHLQQQAQQH----------LQQQQHLAQQQHPHQQHHQAAAAA--------AAL 1537
            :|.|||.:..:...|:|..:          ..:.........|||.:...|||:        :|.
Human     4 EQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSAC 68

  Fly  1538 HHQSMLLTSPGLPPQH------AISLPPSAGGAQPGG-----PGGNQGSSNPSNSEKKPMLMPVH 1591
            ..||   ::|...|.|      ...:.|..|.:|.||     ||.|.....|......|.|.|..
Human    69 SIQS---SAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSS 130

  Fly  1592 GTN---AMRSLHQHMSPTVYEMAALTQDLDTHDITTKIKEALLANNIGQKIFGEAVLGLSQGSVS 1653
            .||   .:.:......|.....:|                     .|.::||
Human   131 PTNPGGGVPAKKPKGGPNASSSSA---------------------TISKQIF------------- 161

  Fly  1654 ELLSKPKPWHMLSIKGREPFIRMQLWLSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTS 1718
                   ||                              ..|.|:.||         |.||..|:
Human   162 -------PW------------------------------MKESRQNSK---------QKNSCATA 180

  Fly  1719 SNDTNDFYTSSPGPGSVGSGVGGAPPSKKQRVLFSEEQKEALRLAFALDPY---PNVGTIEFLAN 1780
            .....|  .|.|||.           ||:.|..::..|...|...|..:.|   |.  .:| :||
Human   181 GESCED--KSPPGPA-----------SKRVRTAYTSAQLVELEKEFHFNRYLCRPR--RVE-MAN 229

  Fly  1781 ELGLATRTITNWFHNHRMRLKQQ-----VPHGPA--------------------GQDNPIPSRES 1820
            .|.|..|.|..||.|.||:.|:.     :.|.||                    ||..|:|....
Human   230 LLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAY 294

  Fly  1821 TSATPFDPVQFRILLQQRLLELHKERMGMSG-----AP----IPYPPYFAAAAILGRSLAGIPGA 1876
            .:.:|  |.            ..|.:..|.|     ||    :|....:||.......:|...|.
Human   295 DAPSP--PA------------FAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGG 345

  Fly  1877 AAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLKRERSDDYQDDLELEGGGH---- 1937
            .|:|....:...|   ||:.::::..|.....:...||.|:   ..|.||....::.|..|
Human   346 FASANLQGSPVYV---GGNFVESMAPASGPVFNLGHLSHPS---SASVDYSCAAQIPGNHHHGPC 404

  Fly  1938 -------NLSDNESLEGQEPE 1951
                   :||.:.|.:|:.||
Human   405 DPHPTYTDLSAHHSSQGRLPE 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527	5/73 (7%)
		Homeobox	1749..1801	CDD:278475	18/54 (33%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..62		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..197		41/224 (18%)
		Antp-type hexapeptide	160..165		4/54 (7%)
		Homeobox	198..250	CDD:306543	18/54 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..280		3/26 (12%)
		DUF4074	369..430	CDD:315871	15/60 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..432		7/26 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910