DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ct and HOXB2

DIOPT Version :9

Sequence 1:NP_524764.1 Gene:ct / 44540 FlyBaseID:FBgn0004198 Length:2175 Species:Drosophila melanogaster
Sequence 2:NP_002136.1 Gene:HOXB2 / 3212 HGNCID:5113 Length:356 Species:Homo sapiens


Alignment Length:282 Identity:66/282 - (23%)
Similarity:103/282 - (36%) Gaps:82/282 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly  1695 ERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGVG----GAPPSKKQRVLFSEE 1755
            |::.|.|      |:|...|...:::     ...:.|.||...|:|    |...:::.|..::..
Human   100 EKKSAKK------PSQSATSPSPAAS-----AVPASGVGSPADGLGLPEAGGGGARRLRTAYTNT 153

  Fly  1756 QKEALRLAFALDPY---PNVGTIEFLANELGLATRTITNWFHNHRMRLKQQVPHG---------P 1808
            |...|...|..:.|   |.  .:| :|..|.|..|.:..||.|.||:.|:|..|.         |
Human   154 QLLELEKEFHFNKYLCRPR--RVE-IAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACP 215

  Fly  1809 AGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPYFAAAAILGRSLAGI 1873
            ...::.....|..:|:|..|...|...:                ...:||..            :
Human   216 GALEDICDPAEEPAASPGGPSASRAAWE----------------ACCHPPEV------------V 252

  Fly  1874 PGAAAA-----------AGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLS--MPTLKRERSDD 1925
            |||.:|           |||::...|:..:||.|...|.:   :..||...|  :|.|....:|.
Human   253 PGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPE---DVFSGRQDSPFLPDLNFFAADS 314

  Fly  1926 YQDDLELEGGGHNLSDNESLEG 1947
            .   |:|.||   ||  .||:|
Human   315 C---LQLSGG---LS--PSLQG 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ctNP_524764.1 CUT 886..955 CDD:280527
CUT 1335..1411 CDD:280527
CUT 1616..1690 CDD:280527
Homeobox 1749..1801 CDD:278475 16/54 (30%)
HOXB2NP_002136.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 39..142 12/52 (23%)
Antp-type hexapeptide 94..99
Homeobox 147..199 CDD:278475 16/54 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 197..240 8/42 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.