DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ct and SPCC364.04c

DIOPT Version :9

Sequence 1:	NP_524764.1	Gene:	ct / 44540	FlyBaseID:	FBgn0004198	Length:	2175	Species:	Drosophila melanogaster
Sequence 2:	NP_587840.1	Gene:	SPCC364.04c / 2539476	PomBaseID:	SPCC364.04c	Length:	633	Species:	Schizosaccharomyces pombe

Alignment Length:	576	Identity:	109/576 - (18%)
Similarity:	203/576 - (35%)	Gaps:	138/576 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 NSHQDEEELDDEEEDEEEDEDEDDEEENASMQSNADDMELDAQQ---ETRTEP-SATTQQQ---- 323
            |:.:.:::::|.::::||.|.....:|....:......|||..:   ||..|. :|.|:::
pombe   115 NNLKTQKQIEDLKKEKEEMEGSLQGKEKLEREVENLRKELDKYKDLVETEAEKRAAITKEECEKS 179

  Fly   324 --HQQQDTEDLE-ENKDAGE------ASLNVSN-NHNTTDSNNSCSRKNNNGGNESEQHVASSAE 378
              .||:..:|:| ||....:      ..|..|. :|:...|.|..:..:.|..:.....:.|..:
pombe   180 WLEQQKLYKDMEQENASTIQKLTSKIRELQASQLDHDLQASQNESAGLDVNAKSAEVNAILSELD 244

  Fly   379 DDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRKKKNNNNNNGQPAVLLAAKDKEIK 443
            |          :|.......|.......|.....||:|:    .:.:|...|....:.:.:|::.
pombe   245 D----------ANKIIVELQAEIAVLKQNTKEQKSGSSQ----DDLSNQQKQQLDFMDSLNKKLS 295

  Fly   444 ALLDELQRL-RAQEQTHLVQIQRLE----EHLEVKRQHIIRLEARLDKQQINEALA--EATALSA 501
            ..|:.::.. |.:.:||...||.||    |..:||.:.:.......|..:|...|:  :....|.
pombe   296 TELESIKEASRKEMETHCATIQTLENEVKEARKVKEESLTLANKFSDYDEIKRELSVLKQIEFSG 360

  Fly   502 AASTNNNNNSQSSDNNKKLNTAAERPMDASSNADL-----PESTKAPVPAEDDEEDEDQAMLVDS 561
            ..:|:.|.:.:|....::...:.|.....|:||.|     .||.||....:...|.|:....::.
pombe   361 EHATHENTSLESQLLKREKQLSEELAKLRSTNAQLTDRITQESKKASFLEQKASEQEEVIRKLEK 425

  Fly   562 EEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKKEQHSPLDLNVLSPNSAIAAAAAAAAA 626
            :.|             |.|.:.....:.||      .::|..|    ..|||.|:|
pombe   426 DLA-------------DVDVEGSVYLSNTT------YRREGTS----GQLSPTSSI--------- 458

  Fly   627 AACANDPNKFQALLIERTKALAAEALKNGASDALSEDAHHQQQQHHQQ----------------- 674
              ...:|:.|...::.|...       |....|: .|...||:...::
pombe   459 --MGGNPSLFNGSVLSRNSV-------NETGSAI-VDVIKQQRDRFRRANVTLVNQVSAANDKIA 513

  Fly   675 --QHQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLHGHGLLHPSSAHHLHHQT 737
              :.:.::.......|::|...                .||:..|       :.|||:   |.||
pombe   514 LLESKLEEVEKSNTLLYEQMRF----------------RDHYQKH-------VEPSSS---HLQT 552

  Fly   738 TESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLNGTKSLMQEDSNGL 793
            ..:..||.:|.|:.....:..:.|  ...|..::..:|..||     |....:.||
pombe   553 AAAYENSISPFASFRKKEAERAYS--RMGSFERIVYALLRTL-----LFSRATRGL 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ct	NP_524764.1	CUT	886..955	CDD:280527
		CUT	1335..1411	CDD:280527
		CUT	1616..1690	CDD:280527
		Homeobox	1749..1801	CDD:278475
SPCC364.04c	NP_587840.1	CASP_C	403..617	CDD:285395	48/274 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001636
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14043
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R168
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.130